2021 Board Review- Allergens and Antigens- (Chapter 9 and selections from Chapters 5)

This is commonly known as 'black mold'. Toxin producing, it can present indoors after water damage

Which of the following is an important advantage to Rotorod samplers?

Health care workers react most frequently to:

Which method of volumetric air sampling can be used to measure dust levels, endotoxins, fungi & microorganisms?

Produces the aflatoxin tenuazonic acid which is nephro/ hepatotoxic. Found in decaying plants/ grain-growing areas.

Which grass sub-family has the strongest cross-allergenicity?

These soybean proteins are Bet v1 homologs and associated with mild symptoms and/or OAS

Individuals predisposed to atopy may be sensitized at mite levels of:

Which of the following Hymenoptera allergens is a Hyaluronidase?

Produced by fossil fuel or natural gas combustion, this is the major outdoor pollutant involved in asthma exacerbations

Hazelnut protein which is a Bet v 1 homolog and associated with tolerance and/or mild OAS

Levels of Fel d1 in environment associated with sensitization and asthma exacerbation, respectively

Which allergen is known to be cross reactive with celery, coriander, peppers, parsley & fennel?

Fungi produces mycotoxins & cause hypersensitivity pneumonitis/ extrinsic allergic alveolitis (EAA) in cheese workers

Wheat protein (aka Omega-5-gliadin) associated with anaphylaxis and wheat-dependent exercise induced anaphylaxis

Which of the following in NOT a standardized unit of potency for immunotherapy extracts?

This tree, in the same family as olive, allergenically important in eastern and central US, Fra a1

Which of the following Hymenoptera allergens is a phospholipase?

This peanut protein is a defensin and may be associated with more severe anaphylaxis

Ray Charles’ ‘Georgia’ refers to moonlight through these trees. Its pollen has air bladders to help it stay airborne.

Approximately what % of flowering plants are anemophilous?

These dust mite allergens are lipopolysaccharide (LPS) binding proteins that activate TLR4 induce airway inflammation

Which of the following is NOT a principle method of volumetric air sampling?

Less water-soluble latex proteins, are more commonly identified as allergens in sensitized spina bifida patients

Which pair of dust mite allergens share the greatest homology?

New onset winter allergic rhinitis Sx after moving to Texas. Which allergen would be least likely to improve new Sx?

To maintain potency allergen extract products should be kept at:

The 5 types of standardized allergen extracts:

Which of the following is an important advantage to slit impactors, such as the Burkard?

This egg allergen is associated with more persistent egg allergy and is the best predictor of reacting to heated egg

Which of the following is an important advantage to Anderson samplers?

This allergen is Cat IgA associated with galactose alpha 1,3 galactose (alpha gal) reactions

This is the tropomyosin allergen in dust mites and cross reacts with other invertebrate tropomyosin (eg shrimp)

Most clinically significant pollens range between what size in diameter?

This shrimp protein is tropomyosin and results in cross reactivity between shrimp, CR and DM

After dust mites, this is the second major source of indoor allergens in the US, found in >90% of U.S. homes

Cat allergen associated with pork-cat syndrome due to cross-reactivity with pork albumin

At what Air Quality Index may sensitive groups first experience 'more serious health effects'?

A lipocalin, 5% of gen pop will test positive despite negative exposure hx. Cross reactive with Fel d 4 and Can f 6.

This major milk allergen is the more heat stable Casein and is associated with more persistent allergy

Which of the following is not one of Thommen's Postulates of Allergenicity?

This heat labile peanut protein is associated with mild symptoms/ OAS and is a Bet v 1 homolog

Which of the following grass allergens have the highest degree of cross-reactivity?