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RMEvBiol_week9

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Questions 8

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1
One way to measure migration between sub-populations is using
the proportion of private alleles
assignment tests
FST , where Nm = (1-Fst)/4Fst
all three methods
2
F_ST is one F-statistic that measures
deviations from HWE in the total population
deviations from HWE within sub-populations
genetic differentiation among sub-populations
3
What do AMOVA's take into account that F-statistics do not
Variation in observed heterozygosity
Variation in observed alelle frequency
Uneven sample sizes
genetic distance between alleles
4
What is the effect of population subdivision on genetic drift?
drift doesnt change
drift increases in each deme
drift decreases in each deme
drift can increase or decrease
5
A positive value for the F-statistic - F_IS - indicates
an excess of homozygote dominant genotypes
an excess of heterozygotes
an excess of homozygotes
significant population subdivision
6
F-statistics measure
mutation rates in sub-populations
deviation of observed heterozygote frequencies from expected under HWE
deviations of observed allele frequencies from those expected under HWE
The distance between E and G
7
One limitation of F-statistics for measuring population subdivision is that
you need to know what you are doing
you need very large sample sizes
observed heterozygosity must be > 0.5
you need to identify sub-populations a priori
8
Under the neutral theory, the probability of fixation for a new mutation in mtDNA is
two times higher than a mutation in autosomal DNA
1/4 that of a mutation in autosomal DNA
1/2 that of a mutation in autosomal DNA
four times higher than a mutation in autosomal DNA