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Pathology Quiz Bowl 2023 Flashcards | StudBud
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Pathology Quiz Bowl 2023
Pathology Quiz Bowl 2023
25 terms
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Questions
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Answers
1
Which variant of focal segmental glomerulosclerosis (FSGS) has the worse prognosis, superseding other variants?
Hilar
Cellular
Tip
Collapsing
2
18 month old child with lesion on face; where is the most common EXTRA cutaneous site involved?
CNS
Bone
Eyes
Lungs
3
This tumor from the skin is positive for neuroendocrine markers and AE1/AE3 (paranuclear punctate staining).
The most common site is on the trunk
Positive for MCPyV stain
The clinical course will be indolent
CK20 expression will be nuclear
4
In changing a new reagent lot, the ISI (international sensitivity index) is not updated - which lab test will be wrong?
PT
aPTT
PT and aPTT
INR
5
28 yo with low urine output for 6 days. UA = 1+ protein, 4+ hematuria. IF shown here, what do you expect on biopsy?
Cellular crescents
Mesangial hypercellularity and nodules
Capillary thrombi
Glom BM spikes
6
Which of the following immunostain profiles is expected in the tumor seen here?
S100+, SOX10+, HMB45+, MelanA+
Desmin+, myogenin+, MyoD1+
S100+, CD68+, TFE3+
S100+, CD1a+, fascin+
7
A midline suprasellar mass is excised from a young patient. What is most likely finding?
Cytokeratin -, Beta-catenin +, BRAF mutated
Cytokeratin +, Beta-catenin -, BRAF mutated
Cytokeratin -, Beta-catenin-, BRAF wild-type
Cytokeratin+, Beta-catenin+, BRAF wild-type
8
Which of the following best characterizes MDS/MPN with ring sideroblasts and thrombocytosis (aka RARS-T)?
Low blast count (<1% in PB, <5% in marrow)
Deletion 5q
Circulating ring sideroblasts >15%
Persistent monocytosis, without secondary etiology
9
Which of the following findings is typical in a patient with DIC?
Elevated plasminogen
Elevated protein C and protein S
Decreased fibrinogen
Thrombocytosis
10
How can we best prevent TA-GVHD in a pediatric patient receiving granulocytes for fungal infection after BMT?
No prevention needed; this patient is not at risk
Leukoreduction
Freeze-thaw cycle
Gamma irradiation
11
The most common gene rearranged in myoepithelial tumors is:
SS18
FUS
ZNF444
EWSR1
12
A 36 year-old man with mild anemia has the blood smear features seen here. What Rh abnormality may also be present?
Partial D
Partial e
Weak D
Rh null phenotype
13
A key feature separating TRALI from TACO is:
Exposure to plasma containing blood products
New pulmonary infiltrates
Hypotension
Decreased O2 saturation
14
Kidney shows acute tubular injury with positive myoglobulin in tubular casts. What is the most likely clinical history?
Myeloma
Rapidly progressive glomerulonephritis
Trauma, extreme physical exercise or prolonged immobilization
Dehydration
15
Dilution of urine samples for drug of abuse testing can be confirmed by measuring:
Urine creatinine
Serum creatinine
Urine electrolytes
Urine volume
16
A pregnant woman is suspected to have an anti-G, as she has anti-D and anti-C. When would RhIG be indicated?
Anti-G, anti-D, and anti-C are detected
Anti-G and Anti C are found, but no anti-D
Anti-G and anti-D are found, but no anti-C
Anti-D and Anti-C are found, but no anti-G
17
Which RBC antigen is considered the receptor for Plasmodium vivax?
P antigen
Lewis
M,N,S (and U)
Duffy
18
Patient with no hx of transfusion has these DAT results. Eluate reacts with 11/11 cells. Which is most likely?
Cold agglutinin disease
Drug dependent RBC antibody
Warm autoimmune hemolytic anemia
Hemolytic transfusion reaction
19
A plasmapheresis patient complains of perioral tingling - which of the following is the likely cause?
Hypocalcemia
Nerve injury during phlebotomy
Hypovolemia
Hyperventilation
20
Subacute panniculitis-like T-cell lymphoma is characterized by:
CD4+ T-cells, high Ki67
CD8+ T-cells, low Ki67
CD8+ T-cells, high Ki67
CD4+ T-cells, low Ki67
21
30 year-old with tibia lesion. What mutation is most likely?
FOS
FUS
KMT2D
ZNF444
22
Which is the marker used for stem cell aquisition during BMT?
CD34
CD45
CD20
CD38
23
Which is the correct association of product and "shelf-life"?
Liquid plasma - 26 days
PF24 - 24 hours
FFP (thawed plasma) - 1 year
FFP (frozen) - 5 days
24
Which of the following is the gold standard for PNH testing?
Peripheral blood smear
Bone marrow biopsy
Coombs test (DAT)
Flow cytometry
25
This cystic lesion is found in the proximal tibia of a young boy. FISH detects USP6 gene rearrangement.
Unicameral bone cyst
Telangiectatic osteosarcoma
Giant cell tumor of bone
Aneurysmal bone cyst