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Haematology Revision Quiz Flashcards | StudBud
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Haematology Revision Quiz
Haematology Revision Quiz
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#Sheffield Phase 2a #Medicine #Haematology Quiz for #Revision
Flashcards
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Questions
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Answers
1
Which of the following is not a recognised cause of multiple myeloma?
Hereditary
High-dose radiation
HIV
Human Herpes Virus-8
2
What is the most likely diagnosis?
Alcohol toxicity
Vitamin B12 Deficiency
Hypothyroidism
Folic acid Deficiency
3
↓B
12
is the most common cause of Megaloblastic anaemia. Why?
B12 upregulates myeloid progenitor making megaloblasts
B12 is responsible for erythroblast enucleation
B12 is necessary for DNA synthesis
B12 affects the progenitor development in bone marrow
4
Clinical features of pernicious anaemia are...
Mild jaundice
All of the above
Glossitis (red sore tongue) and Angular stomatitis
Cardiomyopathy
5
Most likely to get with Maudy next?
Durkin
Mrs MedSoc
Rhi
Molly
6
Which is the most common cause of microcytic anaemia?
Intrinsic Factor deficiency
Sideroblastic Anaemia
Chronic Disease - e.g. Renal Failure
Iron deficiency
7
In which of the following dieases is a massive splenomegaly not a characteristic feature?
Chronic myeloid leukaemia
Infectious mononucleosis
Polycythaemia rubra vera
Thalassaemia
8
What are the potential causes of sideroblastic anaemia?
Isoniazid
All of the above
Lead toxicity
Alcoholism
9
A 55yo Male comes to clinic with Hb = 9.6 and MCV = 77.2. What type of anaemia is most likely?
Normocytic
Microcytic
Pernicious Anaemia
Macrocytic
10
Anaemia of Chronic Disease can be caused by:
TB and CKD
All of the above
Crohn's and Rheumatoid Arthritis
Crohn's and CKD
11
Who's most likely to get married first?
Frazier
Maudy
Mellon
Sam
12
Which investigation would help differentiate between AML and ALL?
Leukocyte alkaline phosphatase
Tartrate-resistant acid phosphatase stain
Sudan black B
Myeloperoxidase stain
13
Pernicious anaemia causes B
12
deficiency how?
Reduction in Intrinsic Factor production
Delta cells increase production of somatostatin
Parietal cell atrophy
Chief cells atrophy
14
Sickle cell offers partial immunity against which infectious disease?
TB
Hep C
HIV
Malaria
15
Which bleeding disorder has the highest incidence?
Haemophilia A
Immune thrombocytopenia purpura (ITP)
von Willebrand's disease
Haemophilia B
16
What would be the first course of action?
Perform immediate coagulation screen and platelet count
D-dimer scan of leg
Vitamin K supplements
Start heparin treatment immediately
17
Erythrocytes originate from which progenitor cell?
Multipotential hematopoietic stem cell
Common lymphoid progenitor
Common myeloid progenitor
Megakaryocyte
18
What is the first line of treatment (see picture for history)?
Treatment of CKD
IM iron
Oral Ferrous gluconate 300mg TDS
Oral Ferrous sulphate 200mg TDS
19
First line treatment of von Willebrand's disease includes:
vWF concentrates
Desmopressin and factor VII concentrates
Factor VII and vWF concentrates
Desmopressin and factor VIII concentrates
20
The most likely diagnosis is:
Idiopathic erythrocytosis
Myelofibrosis
Polycythemia vera
Chronic myeloid leukaemia
21
The most likely diagnosis is:
Acute myeloid leukaemia
Aplastic anaemia
Thrombotic thrombocytopenia purpura
Bacterial infection
22
Macrocytic anaemia is most common in...
Women with fair hair and blue eyes
Women with dark hair and blue eyes
Men with fair hair and blue eyes
Men with dark hair and brown eyes
23
Which blonde has the most fun?
Alice
Penny
Ifor
Lizzie
24
What is the most likely diagnosis?
α-thalassaemia trait
β-thalassaemia trait
Iron deficiency anaemia
anaemia of chronic disease
25
The next Investigation following the results of FBC, would be to...
Serum ferritin
Genetic Test
Serum Iron
Bone marrow biopsy
26
What is the most likely diagnosis?
Disseminated intravascular coagulation
Autoimmune haemolytic anaemia
Thalassaemia Minor
DVT
27
Which bleeding disorder has the lowest incidence?
von Willebrand's disease
Haemophilia A
Haemophilia B
Immune thrombocytopenia purpura (ITP)
28
If a patient presents with iron deficiency anaemia with dyspepsia, what does NICE recommend?
Urgent 2 week Endoscopy
Anti-emetic and Oral Iron gluconate
IM Iron injection
29
What is the liquid component of blood which contains soluble fibrinogen?
water
leukocytes
plasma
protein
30
Most likely diagnosis (see picture for history):
Von Willebrand disease
Immune thrombocytopenia purpura (ITP)
Liver disease
Haemophilia A
31
If you were her GP, next line of action would be to...
Check for anti-intrinsic factor antibodies
Perform a Schilling test
Seek urgent specialist advice from a haematologist
Treat B12 deficiency
32
What initial investigation is done next?
Bone marrow biopsy
PCR
All of the above
Serum B12 Levels
33
What could be the causes of this anaemia?
Iron deficiency, Acute blood loss or B12 deficiency
Thalassaemia and Endocrine Disease
B12 deficiency or excessive alcohol consumption
Iron deficiency, Thalassaemia or Sideroblastic Anaemia
34
What is the first line treatment?
Platelet concentrates
IV Antibiotics
Iron supplements
All of the above
35
What is the most appropriate target international normalized ratio (INR) range?
3-4
1.0
2-3
1-2
36
What is the most appropriate investigation to determine iron store levels?
Serum iron
Serum ferritin
Bone marrow biopsy
Serum transferrin
37
What is the most likely diagnosis (see picture for history)?
Sideroblastic anaemia
Iron deficiency anaemia
Thalassaemia trait
Anaemia of chronic disease
38
Who did you vote for MedSoc Vice President?
Maudy
RON
39
Who has the best facial hair?
Joe Luckman
Sam Allison
Fraser Lim
Feargus Pitcher
40
A 68yo Male comes in with Hb = 11.1 and MCV = 101.2. What type of anaemia is this?
Normocytic
Microcytic
Macrocytic
41
Here is a blood film. What is the likely diagnosis?
Sickle Cell Disease
Megaloblastic Anaemia
α-Thalassaemia
β-Thalassaemia
42
What is a Bence-Jones protein?
Light chain
IgA antibody
IgE antibody
IgG antibody
43
First line treatment of Microcytic Anaemia to Iron defiency is to treat with...
Parenteral iron
Oral Sodium Feredetate 10mL (3 times daily)
Oral Ferrous sulphate 200mg (two to three times a day)
44
What is the most likely diagnosis?
Warfarin therapy
Factor V deficiency
Bernard Soulier syndrome
Von Willebrand's disease
45
What is most likely to be seen on the peripheral blood smear?
Schistiocytes (fragmented RBCs)
Dacrocytes (teardrop shaped cells)
Spherocytes (RBCs that aren't biconcave discs)
Sickle Cells
