What is a symptom of splenomegaly?

Left upper quadrant pain that radiates to left shoulder, It is asymptotic

An oncogene, A gene that codes for a tyrosine kinase

What is an autologous stem cell transplant?

Transplanting the patient's cells to back to themselves

What are even more symptoms of splenomegaly?

Frequent infection, Bleeding, Fatigue

What does the term "left shift" refer to?

Higher percentage of granulocytes than normal

Why does liver cirrhosis cause splenomegaly?

Portal hypertension causes enlargement of spleen

Why are chest x-rays done in diagnosis of leukaemia?

Lymph nodes and thymus can cause mediastinal widening

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Andrew is Tired (poor Andrew)

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A #math #blindquiz to introduce the basics of #algebra to @year8

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Questions 21

Answers

1
What is a symptom of splenomegaly?
Peripheral embolism
Left upper quadrant pain that radiates to left shoulder
Fever
It is asymptotic
2
What percentage of patients are found to survive for more than 5 years in CLL?
>80%
<40%
>70%
50%
3
Which investigations are done to diagnose leukaemia?
FBC
FBI
Chest X-Ray
Blood film
4
What is the most common form of acute leukaemia?
Nobody knows
Acute myeloid leukaemia
Acute lymphocytic leukaemia
They all have the same incidence
5
What is the mechanism of action of dasatinib?
Beta lactam
Tyrosine kinase inhibitor
Factor Xa inhibitor
Folate antagonist
6
What is BCR-ABL?
An oncogene
A gene that codes for a tyrosine kinase
A noncogene
Not a gene
7
What is an autologous stem cell transplant?
Transplanting the cells of a close relative
When patients perform the transplant themselves
Transplanting the patient's cells to back to themselves
Transplanting the cells from a different species
8
When is a lumbar puncture indicated?
In all patients with ALL
When a patient is under 30
When a patient has suspected white cell infiltration of CNS
When a patient has a family history of ALL
9
What is a known risk for for developing CML?
Ionising radiation
Smoking
Alcohol
Microwave exposure
10
What are even more symptoms of splenomegaly?
Confusion
Frequent infection
Bleeding
Fatigue
11
What does the term "left shift" refer to?
Presence of unilateral spurs on red cells
Higher percentage of granulocytes than normal
Bluish appearance of white cells on film
Higher percentage of reticulocytes than normal
12
What do sickle cells indicate?
Sickle cell anaemia
Rake cell anaemia
Scythe cell anaemia
Hatchet cell anaemia
13
Between which two chromosomes does a Philadelphia translocation occur?
8 and 21
7 and 20
10 and 23
9 and 22
14
What can cause splenomegaly?
Infection
Marijuana usage
Liver disease
Trauma
15
What do Heinz bodies and bite cells indicate?
LAPD
F4PD
G5PD
G6PD
16
What do hypersegmented neutrophils indicate?
Non-megaloblastic anaemia
Vitamin B1 deficiency
Iron deficiency
Folate deficiency
17
Why does liver cirrhosis cause splenomegaly?
Increased risk of infection, which can cause splenomegaly
Haematopoietic load of liver shifted to spleen
Compression of splenic vein
Portal hypertension causes enlargement of spleen
18
Why are chest x-rays done in diagnosis of leukaemia?
Chest x-rays are like low level radiotherapy
Lymph nodes and thymus can cause mediastinal widening
To claim more medicare funding
To exclude other differentials
19
Which of the following is not derived from lymphoid cells?
B cell
SK cell
NK cell
T cell
20
What do smear cells indicate?
Acute myeloid leukaemia
Chronic lymphocytic anaemia
Chronic lymphocytic leukaemia
Chronic myeloid leukaemia
21
What is the Philadelphia chromosome associated with?
Chronic myeloid leukaemia
Philadelphia City
Acute lymphocytic leukaemia
Down syndrome

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