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Exam 2 review Flashcards | StudBud
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Exam 2 review
Exam 2 review
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Questions
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Answers
1
Testosterone affect expression
True
False
2
Condition of sex-linked genes in male is called hemizygous
False
True
3
Which of the following is NOT TRUE about maternal effect?
4 o'clock flower is an example of maternal effect
Shell coiling in snail is an example of maternal effect
Offspring shows phenotype expected from mother's genotype
Maternal effect follows Mendelian pattern of inheritance
4
Thomas Hunt Morgan established house fly as model organism for genetics
False
True
5
Germ-line mutations alter gametes and passed to the next generation
False
True
6
Offspring phenotype always matches genotype of mother in maternal effect
False
True
7
Which of the following is not a cause of mutation?
Ionizing and UV light
Tautomers
Intercalators
Nucleotide
8
What is the common dihybrid cross ratio (in Mendelian Genetics)?
9:3:1:3
3:1
9:3:3:1
9
Which statement is NOT true?
PCR reactions need Mg2+
PCR is an artificial way of DNA replication
PCR only amplifies a small segment of DNA
PCR uses DNA polymerase
10
What type of dominance is illustrated when the heterozygote shows an intermediate phenotype between the two homozygotes?
Overdominance
Complete dominance
Incomplete dominance
Codominance
11
Which of the following statement is NOT true about pUC19
Vector causes mutation
Has multiple cloning site within lacZ
Has ampicillin resistance
Have an ori sequence
12
What stage of meiosis is this?
Anaphase 1
Prophase 1
Telophase 2
Anaphase 2
13
Which of the following animals are known to have temperature dependent sex determination?
Reptiles
Birds
Wasps
Fruit flies
14
In blood type genetics, what is the genotype for a person with type O blood?
i/i
IB/IB
IA/IA
IA/i
15
VNTR was first used in which case?
Narborough Murders
Golden State killer
16
Transcriptomics is the study of complete set of RNA transcripts
False
True
17
Methylated DNA protects bacterial genome from RE
False
True
18
Codominance means that the heterozygote exhibits a phenotype that is a blend of both homozygotes.
True
False
19
Mendel's Law of Independent Assortment states that genes for different traits are independent
False
True
20
What does the acronym CRISPR stand for?
Controlled Reservative Image Spectacle Palindromic Recounts
Clustered Regularly-Interspaced Short Palindromic Repeatsp
21
What is the purpose of a complementation test?
To determine if two alleles are dominant.
To determine if mutants affect the same or different genes.
To test if two genes interact.
To analyze if a gene follows Mendel’s laws
22
Oligonucleotide hybridization is a way of finding SNP's
False
True
23
Reverse transcriptase converts cDNA to RNA
False
True
24
What is the term used when a single copy of a gene is insufficient to provide the normal function?
Overdominance
Codominance
Haploinsufficiency
Incomplete dominance
25
Epistasis refers to one gene affecting the expression of another gene.
False
True
26
Somatic mutations occur in sex cells and affect only the individual
False
True
27
Which of the following is not a repair mechanism?
Dichromosomal repair
Base excision repair
Methyl-directed mismatch repair
Nucleotide excision repair
28
Carrier detection, cfDNA screening, prenatal diagnosis, newborn screening are different genetic testing method
True
False
29
Which of the following is not a type of DNA polymorphism?
STR's
SNP's
VNTR's
SRP's
30
Nucleotide excision repair mechanism can remove Thymine dimers
True
False
31
Which of the following is matched correctly?
Southern blot-DNA
Western Blot-RNA
Eastern blot- DNA
Northern Blot- Proteins
32
What is a nonsense mutation?
results in a codon that codes for a different amino acid.
changes a normal codon into a stop codon
Change from an amino acid to another amino acid with similar properties
changes a single nucleotide, but does not change the amino acid created.
33
Pyrosequencing is one of the Next Generation sequencing methods
False
True
34
Product rule is used in independent events (key word: AND)
False
True
35
Which of the following is not a step in PCR
Priming
Translation
Polymerization
Melting
36
What is the function of ddNTP?
Stop extension of DNA strands randomly
Form phosphodiester bond
Acts as a primer
37
Law of segregation states that two forms of a gene segregate during mitosis
False
True
38
How is the structure of dideoxyribose different from deoxyribose
C3 has only H instead of OH
C4 has only H instead of OH
39
In which stage does crossing over of homologous chromosome take place?
Metaphase 2
Metaphase 1
Prophase 1
Prophase 2
40
Which of the following is NOT true about Autosomal Recessive Traits?
Trait usually appear equally in males and females
Likely to appear among progeny of related parents
Trait is common in female than male
Tends to skip generations
41
Cyclin and cyclin-dependent kinases are regulatory molecules in Cell Cycle
False
True
42
Suppressor mutation compensates for the negative effects of the original mutation
True
False
43
WHich of the following is NOT related to CRISPR-Cas9
Cas9 protein
Nuclear sequence
Seed sequence
sgRNA
44
The current "gold standard" for huan DNA typing is STR analysis
True
False
45
Aneuploidy is a result of nondisjunction
True
False
46
Blunt ends are more useful than sticky ends
True
False
47
mambalgin-1 peptide from venom is as effective as morphine in blocking the pain
False
True
48
Who first integrated genetics, development and evolution? (Hint: Mutationist Theories and Hopeful monster)
Black Mamba
Richard Goldschmidt
Kary Mullis
Frederick Sanger
49
A diploid individual can have more than two alleles of a gene.
True
False
50
Darwin believed in "Particulate Inheritance" and not "Blending theory"
False
True
51
Prokaryotic cell reproduce through Binary fission
False
True
52
Restriction enzyme can cut DNA at any sequence
True
False
53
Who discovered transposons (jumping genes)?
Emmanuelle Charpentier
Barbara McClintock
Doudna
Richard Goldschmidt
54
Choose the odd pair
Phenotype: Observable traits
Genotype: Genetic makeup
Dihybrid cross: Cross for one trait
Monohybrid: Cross for one trait
55
Frederick Sanger developed method for sequencing DNA
True
False
56
CRISPR-Cas9 is derived from Streptococcus progenies bacteria
False
True
57
Taq polymerase functions well even at high temperature
False
True
58
___ is a rare, autosomal recessive disorder of DNA repair characterized by sun sensitivity and UV radiation-induced skin
fragile X syndrome
Down syndrome
Xeroderma pigmentosom
59
STR's is also known as micro satellite
True
False
60
Which of the following pair is INCORRECT?
Mitosis: Crossing over of homologous chromosome
Meiosis: reductive division
Autosome: non-sex chromosome
Down syndrome: Trisomy 21
