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MLT 104 Coagulation: 5.6 Automated Coagulation Instrumentation Flashcards | StudBud
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MLT 104 Coagulation: 5.6 Automated Coagulation Instrumentation
MLT 104 Coagulation: 5.6 Automated Coagulation Instrumentation
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1
Widely used to monitor oral anticoagulant therapy (warfarin/ Coumadin)& allows for standardized anticoagulant therapy
PT Testing
INR
2
Photometric principles of coagulation testing
Turbidity
Nephelometry
3
Prothrombin time testing, what is reported in seconds
Critical value: > 50.00 seconds
Normal reference range: 11.0-13.0 seconds
4
Specimen requirements for whole blood in 3.2% sodium citrate
9:1 dilution of blood to anticoagulant
Sample tube must be at least 90% full
5
International sensitivity index (assigned by the manufacturer for each batch of reagents)
INR
ISI
6
What are the three coagulation analyzers
Semi automated
Handheld instrumentation
Automated
7
How many times must you invert the tube
5-10
1-3
8
Inherited and acquired conditions that alter coagulation
Thrombosis
Thrombophilia
9
Exclusive test for factor 7 deficiency
INR
Prothrombin time (PT) testing
10
Why must you centrifuge at 3000 RPM for five minutes
To remove most of the platelets from specimen (platelet poor)
Because that's what we were taught to do
11
With INR, mathematical correction based upon variations and thromboplastin reagents
Manufacturing
Sample preparation
***Geometric***
Geographical
12
Mechanical principles of coagulation testing
Turbidity
Electromagnetic
Impedance
13
What is the handheld instrumentation of the coagulation analyzer
The most common
Point of care
14
Immunologic principles of coagulation testing
Agglutination increases light absorbance proportional to antigen level
Latex coated monoclonal antibodies
A method used for D dimer
15
With specimen requirements, you should not obtain via a heparin lock or any other heparinized line
False
True
16
Coagulation methodologies
Measures in seconds from mixing sample and reagent immeasurable clot
End point detection
Can be ran semi automated or automated depending on instrument
All revolve around detection of Clot formation
17
What are the principles of coagulation testing
photometric (optical)
Mechanical
Immunological
Chromogenic
