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Chapter 21: Immune system Flashcards | StudBud
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Chapter 21: Immune system
Chapter 21: Immune system
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The Human Body in Health and Illness, 7th Edition
Flashcards
55 cards
F
Practice quiz
P
Host live
L
Questions
55
Answers
1
Which is NOT true about antibodies?
Each consist of 4 molecules called antibody monomer
Separated into 5 Ig classes
Polypeptides between sulfur atoms joined by disulfide bonds
Constant(C) regions are identical in different antibodies of the same class
2
Which of the following is NOT considered the
other
first line of defense surface barrier?
Dermcidin
Lysosome
Defensin
Cytokines
3
What marks a cell as
self
as opposed to
non-self
?
MHC's
being a complete antigen
Immunocompetence
APC's
4
Which is the following is NOT a second line of defense?
Plasma cells
Natural killer cells
Neutrophil
Interferon
5
Macrophages derive from monocytes that exit the bloodstream and enter into tissue.
False
True
6
Increased permeability of local capillaries; sweep foreign material to lymph vessels to process in lymph nodes.
Edema
Exudate
Prostaglandin synthesis
Granulomas
7
Complement proteins that coat pathogens to provide handles for phagocyte receptors to bind to.
Basophils
Mast cells
Histamine
Opsonins
8
Humoral immunity acquired by injection of exogenous antibodies from plasma of an immune donor
Naturally acquired passive immunity
Artificially acquired passive immunity
Naturally acquired active immunity
Artificially acquired active immunity
9
Which innate internal eliminate variety of infected/cancerous cell by detecting general abnormalities&promote apoptosis?
Natural killer cell
Fever
Inflammation
Antimicrobial protein
10
Identify the correct order of a lymphocyte life cycle.
Origin→Maturation→2ndOrgans&Circulate→Antigen Bind&Activate→Prolif&Diff
Origin→2ndOrgans&Circulate→ Antigen Bind&Activate→ Prolif&Diff→Mature
Origin→Prolif&Diff→2ndOrgans&Circulate→Antigen Bind&Activate→Mature
Origin→Mature→Antigen Bind&Activate→2ndOrgans&Circulate→Prolif&Diff
11
Which is true about adaptive defense?
Enhances attack on familiar pathogens
Restricted to initial infection site
Recognizes general pathogens
Initiates antibody to undergo proliferation
12
Acts on a cluster of neurons in the hypothalamus to raise body temperature
Exudate
Pyrogen
Interferon
Membrane attack complex
13
Phagocytosis step __: Phagocyte form pseudopods that engulf the particles, forming a phagosome.
Step 4
Step 3
Step 1
Step 2
14
Neutrophils are the big eaters of the phagocytes.
True
False
15
INF used to treat multiple sclerosis
INF alpha
INF beta
16
Humoral immunity acquired by antibodies passed from mother to fetus/infant
Artificially acquired active immunity
Artificially acquired passive immunity
Naturally acquired active immunity
Naturally acquired passive immunity
17
An incomplete antigen, also called haptens, have immunogenicity, but not reactivity.
True
False
18
Neutrophils follow chemical trail.
Leukocytosis
Diapedesis
Margination
Chemotaxis
19
Which is true about innate deffense?
Surface membrane provide immunological memory of pathogens
Works separate from adaptive
Dendritic cells cover proteins which allow a virus to enter our cells
Often prevents infection without help or backup
20
Besides their antiviral effects, interferons activate ___ and mobilize ___.
macrophages; white blood cells
macrophages; natural killer cells
leukocytosis; white blood cells
leukocytosis; natural killer cells
21
Which is NOT true about adaptive defense?
Cellular immunity primarily involves T cells
Humoral immunity is a distinct overlapping area involving T & B cells
Protects from many infectious agents
Antigens are the target of immune defense
22
Which is NOT true regarding the innate defense system?
Has an immediate response to foreign substances
Consists of surface barriers & internal defenses
Inhibits invaders with protective chemicals
Targets specific pathogens located anywhere in the body
23
Which can be considered a first line of defense?
Phagocyte
Enzyme
Lymphocyte
Histamine
24
Complement pathway that coats target cells
Classical pathway
Alternative pathway
Activation pathway
Lectin pathway
25
Lymphocytes are unresponsive to body cells.
Immunocompetance
Self-tolerance
26
A complete antigen has both immunogenicity and reactivity.
False
True
27
Complement pathway that lacks inhibitors on microorganism's surface
Lectin pathway
Alternative pathway
Activation pathway
Classical pathway
28
Which innate internal is a non specific response to any tissue injury with a chemical alarm?
Natural killer cell
Antimicrobial protein
Fever
Inflammation
29
Fluid with clotting factors & antibodies from blood to tissue spaces which sweeps foreign material to lymphatic vessels
Interferon
Pyrogen
Membrane attack complex
Exudate
30
All of the following are considered innate body defenses
except ___.
Antibodies
Lysosomes
Pyrogens
Inflammation
31
Neutrophils enter blood from bone marrow.
Diapedesis
Margination
Chemotaxis
Leukocytosis
32
Bacteria that invade surrounding tissues due to slippery coats of evolved enzymes
which makes adherence difficult.
Streptococcus pneumoniae
Mycobacterium tuberculosis
33
Humoral immunity acquired by vaccine; dead or attenuated pathogens
Artificially acquired passive immunity
Artificially acquired active immunity
Naturally acquired active immunity
Naturally acquired passive immunity
34
Receptors recognize an antigen & lymphocytes react to one distinct antigen determinant.
Self-tolerance
Immunocompetence
35
Group of plasma proteins that circulate through blood in an inactive state to amplify inflammation
Membrane attack complexes
Complement
Opsonization
Interferons
36
Which is NOT a way that respiratory bursts promotes killing pathogens?
^ phagolysosome pH & osmolarity, which activates protein-digesting enzymes
Prevents the spread of damaging agents to nearby tissue
Producing oxidizing chemicals ex. hydrogen peroxide
Liberating a deluge of highly destructive free radicals
37
Look for lack-of-self receptors by recognizing certain surface sugars on the target cell:
Phagocytes
Natural killer cells
Interferons
Antimicrobial proteins
38
Why is the secondary immune response faster than the primary immune response?
Secondary response is the initial encounter
Primary response is faster than secondary response
Secondary response has low plasma levels
Secondary response recognizes familiar antigens
39
Phagocytes infiltrate injured sites as an inflammatory response so tissue repairs.
Interferon mechanism
Opsonization
Phagocyte mobilization
Phagocytosis
40
Small proteins secreted by virus
infected body cells to protect nearby cells that have not yet been infected.
Interferons
Membrane attack complexes
Exudate
Pyrogens
41
Phagocytosis step __: Sometimes exocytosis of the vesicle removes indigestible and residual material.
Step 3
Step 5
Step 2
Step 4
42
Antiviral proteins block viral reproduction to help protect cells that have not yet been infected.
Phagocytosis
Phagocyte mobilization
Interferon
Opsonization
43
Complement pathway that binds to specific sugars on a microorganisms surface
Lectin pathway
Alternative pathway
Activation pathway
Classical pathway
44
Which innate internal is a localized response to infection, but body response is sometimes more widespread?
Fever
Inflammation
Antimicrobial protein
Natural killer cell
45
Neutrophils flatten and squeeze out of capillaries.
Leukocytosis
Margination
Chemotaxis
Diapedesis
46
Self identification proteins on your cell membranes
Antigenic determinants
Major histocompatibility complexes
Antigen-presenting cells
Clonal selection
47
Protein forms & stabilizes a hole in the membrane to allow a massive influx of water
Pyrogen
Membrane attack complex
Exudate
Interferon
48
Phagocytosis step __: Lysosome fuses with the phagocytic vesicle, forming a phagolysosome.
Step 4
Step 2
Step 5
Step 3
49
Humoral immunity acquired by infection from contact with a pathogen
Artificially acquired passive immunity
Artificially acquired active immunity
Naturally acquired active immunity
Naturally acquired passive immunity
50
Phagocytosis step __: Toxic compounds and lysosomal enzymes destroy pathogens.
Step 3
Step 4
Step 5
Step 2
51
Phagocytosis step __: Phagocyte adheres to pathogens or debris (using receptors).
Step 3
Step 4
Step 2
Step 1
52
Receptors⇄pathogens→Engulfed particles» phagosome→Lysosome⇄to»Pahogolysosome→Enzymes destroy→ Sometimes exocytosis
Opsonization
Phagocyte mobilization
Phagocytosis
Interferon mechanism
53
Molecule with two identical halves formed by four polypeptide chains
C region stem
Antigenic determinant
Antigen-binding site
Antibody monomer
54
Inflammation does all of the following
except
___.
Tissue repair to promote healing
Disposes of debris
Increases clotting protein to decrease blood flow
Seals off the area to inhibit spread of microbes
55
Neutrophils cling to capillary wall.
Margination
Chemotaxis
Leukocytosis
Diapededis