YEAR 2 end-of-year quiz 23-24

Glutamic acid decarboxylase antibody is seen in which type of diabetes?

When is breast cancer screening checked?

What is shown here?

What is the following ECG showing

Which of the following is responsible for transporting iron out of the enterocyte in the basolateral membrane?

Which of the following is a key characteristic of rheumatoid arthritis joint inflammation?

Which of the following is a cause of macrocytic megaloblastic anaemia

A patient complains of facial pain secondary to a compressed trigeminal nerve. What is the 1st line treatment

Which of the following is a clinical feature of iron deficiency anaemia

This patient sustained a traumatic brain injury. What is the most likely diagnosis?

What is the treatment for type 1 hypopituitary failure?

Which of the following correctly describes the venous drainage below the pectinate line in the rectum

Dutasteride and finasteride can be given for BPH

Which of the following clinical examination finding would expect to elicit in someone with pneumonia

Which of the following medications is commonly used for the treatment of osteoporosis?

Which of the following blood film finding would you expect to see in pernicious anaemia show?

Disease in which part of the gut is most likely to result in vitamin B12 deficiency

Which of the following test can be used to diagnosis Cushing's syndrome

Which of the following protein is responsible for regulating iron homeostasis in the presence of excess iron in the body

What is the most appropriate initial management for ascites secondary to liver cirrhosis?

What is seen in type 2 respiratory failure?

What is the most common genetic mutation in hypertrophic cardiomyopathy

Which of the following best describes the mechanism of action of benzodiazepines?

Which of the following is NOT a tumour suppressor gene in wilms tumour?

What does this EEG show?

Which of the following is a feature of Addisons disease?

Which diuretic is associated with hypovolemia, hypokalemia, hypomagnesaemia and hypercalcemia?

What type of shock can tension pneumothorax result in?

Haematinics reveals a reduced haemoglobin along a normal MCV, what is the most likely underlying diagnosis

What drug should be given for radiotherapy side effects?

Which of the following term describes the placenta inserting into the lower uterine segment (instead of upper segment)

Which of the following is a common dietary recommendation for individuals with gout?

A 65 year old man with a history of ischaemic heart disease is found unresponsive. An ECG is taken, what is shown?

Mutation in which gene is seen in sickle cell disease

A baby is brought into A&E due to poor activity level. Baby looks blue on examination. What is the most likely diagnosis

Which of the following STIs is caused by a virus and can increases risk of cervical, anal, and oropharyngeal cancer?

What type of cardiomyopathy is characterised by the presence of abnormally stiff heart wall causing HFpEF

A 22 week old baby has a normal head circumference but all other parameters are low for his age. What does he have?

Which is a common clinical manifestation of stroke characterized by sudden paralysis of one side of the body?

What is the oncogene for skin cancer?

What is the primary antiviral medication used for the treatment of genital herpes?

A 50 y/o caucasian men with known heart failure has a clinic BP of 145/80. What should be the next course of action?

What is this?

A patient presents with contralateral sensorimotor loss below waste & urinary incontinence. What is most likely?

Which medication is commonly used for the prevention of future gout attacks?

80 y/o patient presents with pneumonia. Fully alert, SpO2 95%, RR 25, HR 110, BP 105/70, urea 6.8. Management?

When is the MMR vaccine given

Which biologic agent targets TNF-alpha and is commonly used as a second-line treatment for RA

Which type of MS is characterized by periods of relapse and remission, with new/worsening neurological symptoms followed

Which coronary artery is most likely to be occluded here?

What ejection fraction would you expect to see in a patient with a history of ischaemic heart disease

A patient has kluver bucy syndrome. What are the most likely features?

Which of the following is a characteristic feature of dermatomyositis but not polymyositis?

Rupture of the middle meningeal artery will result which of the following

Leptin inhibits POMC/CART and activates NPY/AgRP

What drug can cause this side effect?

Which of the following is the most important side effect of clozapine

Which of the following is a clinical sign would be indicative of chronic liver disease secondary to alcoholism

What is tamoxifen

What is the most common cause of primary hypothyroidism?

Which part of the adrenal gland secretes testosterone?

What is the mechanism of action of sulfonylureas

What is a well known side effect of pyrazinamide?

What enzyme converts L-dopa into dopamine

What does the truncus arteriosus develop into?

Which of the following describes when the placenta has invaded into the myometrium of the uterus, but not beyond?

Which of the following anti-anginal drugs are used to reduce heart contractility?

In inclusion body myositis, there is decrease in creatine kinase and a loss of the quadriceps reflex

Which type of pain is characterized by abnormal pain sensations arising from normally non-painful stimuli?

A fit and well 31 year old man presents for a routine insurance medical. This is his ECG. What is shown?

Which of the following is a cause of normal anion gap metabolic acidosis

Which of the following anti-epileptic drug should NOT be used in absence seizures

What is Hirschsprung disease?

In the non amyloidgenic pathway, what is involved?

Damage to the Wernicke's area in the brain is associated with which language disorder?

What gram negative diplococci can lead to septic arthritis?

In the plateleg plug formation. How do platelets bind to VWF?

Iodine in transported into follicular cells through the pendrin ion transporter

Which of the following antihypertensive medications is most commonly associated with a dry cough as a side effect?

Which genetic marker is strongly associated with an increased risk of developing rheumatoid arthritis?

What fracture is shown?

What is seen in alpha thalassaemia when 3 alpha genes and what anaemia could this lead to?

What is "bull neck" most commonly seen in?

MOA of tigabine is inhibition of GAT-1 transporter leading to increase of GABA in synapse

First line treatment for HFrEF

Which of the following is secreted by the anterior pituitary gland

Which of the following is the best description of conjugated bilirubin

A patient with a history of depression and extreme addiction to nicotine is prescribed a drug to combat both. What is it