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Molecular Genetics
Molecular Genetics
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BTHS Mr. Bacchi Molecular Genetics Test Review
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Questions
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Answers
1
Which of the following does not affect gene expression in eukyarotic cells?
The existence of repressor proteins
The compactness of the DNA
The addition of a methyl group
The selection of what genes are treated as introns
2
Which statement is the LEAST likely reason that describes why mutation frequency is low
Drastic mutations are quickly removed from gene pool
Some undesirable phenotype prevents reproduction
The rate of mutation results in ongoing variability
Some mutations produce recessive alleles
3
Which of the following describes the correct enzyme order in DNA replication?
Helicase, Ligase, RNA primase, DNA polymerase
RNA primase, DNA polymerase, ligase, helicase
Helicase, DNA primase, DNA polymerase, ligase
DNA polymerase, RNA primase, helicase, and ligase
4
Where is the anticodon on a tRNA?
Right
Top
Bottom
Left
5
What is the anticodon of an UAC codon
AUG
AUC
ATT
ATG
6
T or F: Prokaryotic cells have more ways to control their gene expression than Eukaryotic cells
Answer 1 and 2
Choice 10 Answer 3 2019 Ap Test
True
False
7
How many proteins can be created from a 21-base message of a mRNA?
21
3
7
42
8
E.Coli's lac operon is dependent on the RNA polymerase's ability to bind in advance. This is
Bacterial regulation
Pre-Translation Regulation
Pre-Transcription Regulation
Post-Transcription Regulation
9
Who officially discovered the double helix of DNA?
Watson, Crick, and Franklin
Erwin Chargaff
Reji Okazaki
It is I, James Bacchi, who discovered it 2019 years ago
10
The mRNA protects it self from degradation by
Having telomeres on both ends
Having a 5' phosphate cap and a poly-T-tail
Colluding with E.coli and staging a coup against the nucleus
Having a 5' GTP cap and a poly-A-tail
11
After splicing, the mRNA goes to the
Nucleus
Ribosome
Golgi Body
Lysosome
12
Which of the following mutations will always shorten the protein created?
Nonsense mutation
Missense mutation
Duplication
Silent mutation
13
Which of the following about DNA replication is not correct?
Each base is paired with another base exactly like it
Semiconservatism replication pairs an old and a new strand
Unwinding of DNA occurs as the hydrogen bonds break
DNA polymerase III catalyzes DNA replication
14
Tryptophan operons are controlled and regulated by
Tryptophan-repressor protein complex
Negative feedback
Positive feedback
The existing attachment of a repressor protein
15
Leading Strand: Lagging Strand is similar to Template Strand: _______
Non-Template Strand
Copying Strand
Processing Strand
Coding Strand
16
Hardest Question: Do you like bio?
Oui
Yes
Jigglypuff
是
17
_______ increases the speed of transcription
TATA box
Promoter
Enhancer
Steroids
18
On what exact region does a repressor protein bind to?
Operon
DNA polymerase
RNA polymerase
Operator
19
Which enzyme is missing if the Okazaki fragments do not combine?
Helicase
DNA polymerase
DNA ligase
RNA primase
20
Which of the following are examples of a frameshift mutation?
Insertion and deletion
Missense, silent, and nonsense
Translation and transcription
Answer A, B, and C
21
What is an inducible operon?
An operon that requires the genes to be turned on
Always anabolic reaction
An operon that requires the genes to be turned off
Always catabolic reaction
22
In which direction is the new DNA made during DNA replication
3' to 5' in leading strand and 5' to 3' in lagging strand
5' to 3'
3' to 5'
3' to 5' in leading strand
23
Heterochromatin is
Loosly packed RNA
Loosely packed DNA
Tightly packed DNA
Tightly packed RNA
24
In DNA replication, which of the following does NOT occur?
DNA polymerase elongates both strands of DNA
Helicase unwinds the double helix
DNA grows from the 5' to the 3'
DNA ligase links the Okazaki fragments
25
The most direct reason that silent mutation is only possible because of
There are 20 amino acids while 64 codons are possible
Third-Base Wobble
Other mutations can fix this mutation
A mutation proof system
26
The four bases of DNA are
Guanine, Adenine, Cytosine, and Thymine
Uracil, Cytosine, Thymine, and Guanine
Cytosine, Adenine, Guanine, and Nucleotides
Cytosine, Adenine, Cytosine, and Guanine
27
Which correctly describes the shape of a tRNA?
Clover-shaped with the amino acid on the bottom
Clover-shaped with the amino acid on the right
Clover-shaped with the amino acid on the top
Clover-shaped with the amino acid on the left
28
Which best describes an operon?
A group of regulating and related genes in all cells
A group of regulating and related genes in eukaryotes
A group of regulating and related genes in prokaryotes
A group of regulating and related genes in plant cells only
29
What type of a mutation is sickle-cell anemia?
Frameshift mutation
Radiation
Point mutation
I didn't study
30
What amino acids does UAUUUUGAG code for?
Tyr, Phe, Glu
Stop
Tyr, Phe, Asp
Tyr, Leu, Glu
31
Euchromatin is
Loosly packed RNA
Tightly packed DNA
Loosly packed DNA
Tightly packed alleles
32
If a cell can add nucleotides in both the 5' to 3' and 3' to 5' directions, ___ will not appear
Okazaki Fragments
Replication Fork
Nicked DNA by topoisomerases
Primer
33
In the post-translational modification, the polypeptide is altered such so that it results in
Excision of introns
A change in the overall conformation of a polypeptide
Formation of a peptide bonds
Addition of poly-A-tail
34
DNA to RNA to Protein best describes which of the following?
Protein Synthesis
Endocrine System of a Cell
The Central Dogma of Biology
An anabolic reaction
35
A repressor protein regulates gene expression because
It...just...works...
It attaches to the TATA box and covering the entire TATA box
It blocks transcription
It blocks translation
36
In which direction is DNA read during DNA replication
5' to 3' in leading strand and 3' to 5' in lagging strand
5' to 3'
3' to 5'
5' to 3' in lagging strand
37
Which enzyme reviews the replicated DNA to prevent mutation?
DNA Helicase
DNA Ligase
DNA Primase
DNA Polymerase II
38
Pre-mRNA has not yet experienced
The removal of all introns
Mutation
Addition of 123456789 more intron codons
Splicing