CVM 741: Lectures 41, 42, 43

Question 1

Reactions that are unpredictable and difficult to prevent

Accepted Answer

Idiosyncratic

Question 2

In a constant rate infusion, the rate of infusion is equal to the rate of elimination.

Accepted Answer

TRUE

Question 3

What is the purpose of the DEA?

Accepted Answer

All of the above

Question 4

Which medications would decrease the production of stomach acid?

Accepted Answer

Antacids, Omeprazole, Famotidine, H2-antihistamines

Question 5

WOTF PK/PD profiles would be time-dependent?

Accepted Answer

Beta-lactams, Clindamycin

Question 6

Induced unintentionally by a vet through their diagnosis, manner, or treatment

Accepted Answer

Iatrogenic

Question 7

WOTF is a security feature build into a prescription pad to prevent forging or tampering?

Accepted Answer

High security watermark on reverse side, Hidden security "VOID" appears when photocopied, Secure scripts have "coin reactive" ink, Tamper resistant background ink

Question 8

An adverse drug event report should include:

Accepted Answer

Recent surgeries/procedures, Good medical history, Names & amounts of all drugs, products, or vitamins, Current type/brand of pet food and treats

Question 9

Veterinary telemedicine shall only be conducted w/in an existing VCPR

Accepted Answer

TRUE

Question 10

WOTF is true regarding a repeated dose schedule?

Accepted Answer

If dosing interval is long enough, there is no additive effect, Plasma conc. falls at elimination rate until next dose, Max plasma conc. is seen @ peak absorption, If plasma conc. still measurable, this produces additive effect

Question 11

___gastric pH->decrease acid->decrease absorbption of weak acids

Accepted Answer

increase in

Question 12

WOTF is the correct equation to calculate infusion rate?

Accepted Answer

R = Css x Vd x k

Question 13

WOTF needs to be met to establish a VCPR?

Accepted Answer

Vet is personally acquainted w/ the keeping & care of the pt, Vet has sufficient knowledge of pt to make a diagnosis, Vet provides oversight, treatment, compliance, and outcome, Vet has assumed responsibility to make clinical judgments for the pt

Question 14

What are the different forms of ADRs?

Accepted Answer

Delayed ADR, Chronic ADR, End of treatment ADR

Question 15

Schedule III-V substance prescriptions can be refilled up to ___ w/in 6 months after it was issued

Accepted Answer

5 times

Question 16

If you are prescribing an opioid for more than 7 days, then you are required to report it.

Accepted Answer

TRUE

Question 17

What is the difference b/t an adverse drug event and an adverse drug reaction?

Accepted Answer

Event: undesired side effect whether or not determined to be caused by drug, Reaction: obtain understanding of a cause & effect from drug

Question 18

A schedule III-V substance can have a prescription filled out in which form?

Accepted Answer

Electronically, In writing, By fax, Orally

Question 19

WOTF is an AVMA guideline for a presctiption label?

Accepted Answer

Dosage and duration, Name, address, & phone # of vet, Date of treatment, prescribing, or dispensing of drug, Name, active ingredient, & quantity of drug

Question 20

What are time dependent antibiotics?

Accepted Answer

The amount of time the drug is above the MIC

Question 21

Use of a compound preparation should be limited to?

Accepted Answer

Safety, efficacy, & stability are demonstrated in compounded form, Disease for which a quantifiable response to therapy can be monitored, Patients where no other method/route of drug delivery is practical

Question 22

Varying the rate of infusion ______the time to reach a steady state.

Accepted Answer

Does not change

Question 23

Dosing quantities will only have an effect on the AUC and Cmax.

Accepted Answer

TRUE

Question 24

When would an extralabel drug be used?

Accepted Answer

Extralabel use to enhance production is not permitted, Limited to circumstances when health of a pt is threatened, When suffering or death may result from failure to treat

Question 25

What are characteristic(s) of an ideal drug?

Accepted Answer

Efficacious, safe, Selective, reversible, Ease of administration, low cost, predictable, chemical stability

Question 26

What are the different types of drug interactions?

Accepted Answer

Pharmacokinetic - plasma/tissue levels altered, Pharmaceutic - chemical/physical interactions of drugs mixed in vitro, Pharmacodynamic - action/effect is altered

Question 27

Change of ____ is not proportional to time of efficacy.

Accepted Answer

dose

Question 28

Do veterinarians have a national provider identifier?

Accepted Answer

Nope

Question 29

Abbreviations (bid, qid) do not increase potential for mistakes to occur

Accepted Answer

FALSE

Question 30

Drugs should never be mixed in a syringe/added to parenteral solutions unless components are compatible

Accepted Answer

TRUE

Question 31

WOTF is the correct way to write a prescription label that's dispensed in a clinic?

Accepted Answer

Cephalexin 250mg - Give 1 capsule by mouth every 8 hours for 7 days.

Question 32

WOTF is a law that must be followed for schedule II substances?

Accepted Answer

No refills, 6 month federal time limit where prescription must be filled, Written prescription which must be signed by a practitioner

Question 33

This term refers to the use of an approved drug in a manner that is not in accordance w/ approved label directions

Accepted Answer

Extralabel Drug

Question 34

Which medications would increase stomach motility?

Accepted Answer

Metoclopramide, Cisapride

Question 35

A VCPR can solely be established by telephone or other electronic means

Accepted Answer

FALSE

Question 36

WOTF is the correct equation to calculate loading dose?

Accepted Answer

D = Vd x C0

Question 37

WOTF affects both steady state levels & difference of Cmax-Cmin

Accepted Answer

Dosing quantity, Dosing frequency

Question 38

What are the different forms of ADEs?

Accepted Answer

Allergy or Hypersensitivity ADE, Dose Related ADE, Idiosyncratic ADE

CVM 741: Lectures 41, 42, 43

Questions 38

CVM 741: Lectures 41, 42, 43

Questions 38