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Cell Neuro (SI) Practice Exam 2 Questions Flashcards | StudBud
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Cell Neuro (SI) Practice Exam 2 Questions
Cell Neuro (SI) Practice Exam 2 Questions
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1
Adding what to Exp 2 reinforced the idea that voltage-gated Ca++ channels are responsible for neurotransmitter release?
Copper
Palladium
Chromium
Cadmium
2
What number of events are observed at the miniature endplate potential?
16
12
20
18
3
Which of the following types of transmission would be the fastest?
Electrical transmission with 2nd messengers
Chemical transmission with ionotropic receptors
Chemical transmission with metabotropic receptors
Electrical transmission with gap junctions
4
Injection of a current into cell A generates a depolarization of 20 mV and 4 mV in cell B. What is the coupling coeff?
5 mV
2 mV
0.2 mV
0.5 mV
5
Activation of AMPA receptors at the synapse:
All of the above
Elicits mixed Na+/K+ flux across the membrane
Generates a membrane current that reverses at 0 mV
Causes depolarization of postsynaptic membrane
6
If a synapse has a large number of gap junctions as well as little resistance, which of the following is true?
It will have a higher coupling coefficient
It will have a lower coupling coefficient
It will have a greater conductance
No action potentials will be generated by this synapse
7
The AMPA and NMDA receptors are permeable to the same ions except NMDA is also permeable to:
Na+
Cl-
Ca++
K+
8
How many quanta of neurotransmitter are released to produce an end plate potential that is 1.6 mV in amplitude?
4
3
2
5
9
Based on the graph, which direction is the membrane current at -20 mV?
Not enough info is given to determine this
Inward
The current is 0
Outward
10
The amplitude of the miniature endplate potential is:
0.8 mV
0.4 mV
1.2 mV
1.6 mV
11
The cell recorded has an RP of -65 and an AP threshold of -59. How many quanta of NT must be released to generate an AP?
7
1
3
15
12
Syntaxin is the protein that coats the internal surface of the plasma membrane to initiate endocytosis.
False
True
13
If sodium and potassium have no driving force (no arrow), then this means that they are at equilibrium potential.
False
True
14
Which of the following neurotransmitters is released at the NMJ (neuromuscular junction) synapse?
GABA
Glutamate
Acetylcholine
Glycine
15
Which of the following is NOT an ionotropic receptor for glutamate?
NMDA
AMPA
GABA
Kainate
16
GABA receptors are inhibitory and are responsible for all the following EXCEPT for:
Shifting membrane potential away from its threshold value
Generating an outward current
Blocking the shunting of membrane currents
Hyperpolarizing membrane potential
17
Shunting inhibition allows for current to flow from the soma (cell body) to the axon hillock.
True
False
18
Based on the graph, which curve depicts the response of synapse with only NMDA receptors in the absence of Mg?
Curve B
Neither Curve A nor B
Both Curve A and B
Curve A
19
Chemical synaptic transmission occurs via:
Activation of a voltage-gated channel
Release of a transmitter from the presynaptic to the postsynaptic neuron
Electronic coupling
Activation of a ligand-gated channel
20
Curare and atropine act by which mechanism on their respective receptors?
As an allosteric antagonist
As an allosteric agonist
As a competitive agonist
As a competitive antagonist
21
Which of the following is the major excitatory neurotransmitter in the PNS?
GABA
Glycine
Glutamate
Acetylcholine
22
Based on the graph, which curve depicts the response generated by a synapse with only AMPA receptors?
Both Curve A and B
Neither Curve A nor B
Curve B
Curve A
23
Based on the graph, what is the reversal potential of this current?
-70 mV
0 mV
-40 mV
800 mV
24
Which of the following is a major excitatory neurotransmitter in the CNS?
Acetylcholine
Glutamate
GABA
Glycine
25
The receptors activated by the neurotransmitter released at the NMJ (neuromuscular junction) are:
2nd-messenger gated
Metabotropic
Nicotinic
Muscarinic
26
What is the main mechanism by which calcium enters the pre-synaptic neuron?
Voltage-gated Na+ channels
Voltage-gated Cl- channels
Voltage-gated K+ channels
Voltage-gated Ca++ channels
27
Based on the graph, which curve depicts the response generated by a synapse with only NMDA receptors?
Both Curve A and B
Curve B
Curve A
Neither Curve A nor B
28
Which of the following is a calcium-sensitive vesicle protein responsible for embedding itself into the plasma membrane?
SNAP-25
Syntaxin
Synaptobrevin
Synaptotagmin