stud
bud
Sign up
Log in
Home
Library
Explore
SAT
More
Pharm block 1 Flashcards | StudBud
Explore
/
Pharm block 1
Pharm block 1
95 terms
·
StudBud Administration
·
7 plays
Imported from external platform
Flashcards
95 cards
F
Practice quiz
P
Host live
L
Questions
95
Answers
1
Who assigns the generic name for a drug? (2-13)
USAN
DEA
the company
FDA
2
Which indirect-acting cholinergic agonist would you caution prescribing to someone with peptic ulcer disease? (4-25)
Physostigmine Salicylate (Antilirium)
Edrophonium (Tensilon)
Neostigmine (Prostigmine, Bloxiverz)
Betanechol (Urecholine)
3
b-blockers are irrevesible. (5-64)
False
True
4
Which of the below is an approved use of gapapentin? (1-8)
fibromyalgia
restless leg syndrome
seizures
social anxiety disorder
5
What clinical use might you use Dobutamine (Dobutrex)? (5-29)
cardiac/septic shock
eye redness and congestion
Acute Decompensated Heart Failure
3rd degree AV block
6
Pt has a creatinine clearance of 23 mL/min and their normal dose of levoflaxin is 500/day. What would change? (3-56)
500 initial, 250/day
500 initial, 250 every 2 days
no change
250/day
7
Ibuprofen is an example of what? (1-13)
chemical name
generic name
brand name
pharmacologic category
8
An endocrine gland secretes its products into a duct. (4-7)
True
False
9
Which drug has the quickest induction speed? (6-15)
Nitrous Oxide
Desflurane
Sevoflurane
Isoflurane
10
A patient can take Carvedilol (Coreg) with food in order to reduce the risk of what? (5-69)
myocardial infarction
angina
orthostatic hypotension
asthma
11
Which schedule of drug does testosterone fall under? (1-34)
V
III
IV
II
12
Which schedule of drug has effects described as "limited physical or psychological dependence"? (1-34)
V
III
IV
II
13
Which type of medication is given to facilitate amnesia during an operation? (6-6)
benzodiazepines
antiemetics
anticholinergics
opioids
14
Pilocarpine (Isopto Carpine) is used to elicit what? (4-16)
reduce aqueous humor
near vision
increase intraocular pressue
radial muscle contraction
15
B2 agonists have a greater efficacy for COPD. (4-52)
False
True
16
All full-service MTFs are required to ensure these medications are available. (1-53)
basic core formulary
uniform formulary
extended core formulary
non-formulary
17
In which phase of drug development is the goal to gather data on efficacy, safety, and dosage using a small group?(1-57)
III
IV
II
I
18
Which drug can cause rhabdomyolysis in healthy pediatric patients? (6-36)
Atracurium
Cisatracurium
Pancuronium
Succinylcholine
19
What is the only noncompetitive acetylcholinesterase inhibitor used for on a regular basis? (4-28)
myasthenia gravis
insecticide
glaucoma
nonobstructive GI/GU tract
20
What side effect are you most likely to experience while using Scopolamine (Transderm Scop)? (4-54)
drowsiness
tachycardia
diarrhea
xerostomia
21
Which of the below are risks associated with toxicity of inhaled anesthetic agents? (6-17)
hyperthermia
hepatotoxicity
megaloblastic anemia
macrocytic anemia
22
An example of phase II metabolism reaction: (3-37)
sulfation
hydrolytic
reductive
oxidative
23
Acetylcholinesterase inhibitors act on acetylcholine receptors in what way? (4-6)
noncompetitive antagonist
competitive antagonist
inverse agonist
indirect agonst
24
If you are looking to treat diarrhea, what receptor antagonist would you choose? (4-34)
M
Nn
Nm
25
What kind of adrenergic agonist is the precursor for methamphetamine? (5-52)
mixed-action
indirect-acting
direct-acting
26
Isoproterenol (Isuprel) causes excitatory effects. (5-27)
True
False
27
Trihexyphenidyl (Artane) is used to treat what? (4-57)
Parkinson's
Alzheimer's
Glaucoma
Myasthenia Gravis
28
What is a drug that binds to the same receptor as an agonist but induces an opposite pharmacological response? (3-83)
indirect agonist
competitive antagonist
noncompetitive antagonist
inverse agonist
29
This occurs as a result of to continuous prolonged exposure of receptors to drugs. (3-89)
hypersensitivity
hyposensitivity
desensitization
supersensitivity
30
Quantal response is defined as the number of subjects showing an "all-or-nothing" response. (3-76)
False
True
31
When using Formoterol (Foradil), what do you have to worry about becoming too low? (5-40/42)
glucose
calcium
blood pressure
potassium
32
When treating benign prostatic hypertrophy with Tamsulosin (Flomax), what adverse effect is not reversible? (5-61/62)
inhibition of ejaculation
2nd or 2rd degree heart block
intraoperative floppy iris syndrome
dizziness
33
Cardiac cells are an example of what muscarinic receptors? (4-7)
M3
M1
M2
34
Which drug has the quickest recovery? (6-15)
Sevoflurane
Isoflurane
Nitrous Oxide
Desflurane
35
You prescribe a drug for incontinence. Patient reports constipation side effect. What drug was most likely given? (4-47)
Solifenacin (Vesicare)
Oxybutynin (Ditropan)
Darifenacin (Enablex)
Fesoterodine (Toviaz)
36
Which drug is the least common (of the ones provided) to cause methemoglobinemia? (6-46)
Ropivacaine
Benzocaine
Prilocaine
Lidocaine
37
Which drug can be used as an off-label treatment for Tourette Syndrome? (5-37)
Midodrine (ProAmatine)
Brimonidine (Alphagan)
Oxymetazoline (Afrin)
Clonidine (Catapres)
38
Which drug regulation requires pharmacists to offer counseling to Medicaid patients? (1-49)
1996 Health Insurance Portability and Accountability Act
1990 Omnibus Budget Reconciliation Act
1962 Kefauver-Harris Amendment
1987 Prescription Drug Marketing Act
39
Which cholinergic agonist would you need to monitor for seizures? (4-24)
Neostigmine (Prostigmine, Bloxiverz)
Betanechol (Urecholine)
Edrophonium (Tensilon)
Physostigmine Salicylate (Antilirium)
40
You are faxing a prescription for a hospice patient. What must you remember to note on it? (1-38)
that it is a Medicare pt
that it falls under Title 93
nothing - faxing isn't valid
that it is a hospice pt
41
At high doses, what effects would you expect from Epineprhine? (5-22/13)
increase urinary retention
inhibit insulin release
increase release of glucagon
increase renin secretion
42
What routes can Ketamine (Ketalar) be administered? (6-24)
PO
IV
IM
IN
43
What best describes how the drugs that are given to Alzheimer's Disease patients work in the CNS? Name one. (4-31)
inhibit acetylcholine; Rizedine
inhibit acetylcholinesterase; Aricept
prolong acetylcholinesterase; Excelsior
prolong acetylcholine; Conex
44
You could expect a drug interaction between Pseudoephedrine (Sudafed) and what other drug? (5-52/55)
Phentolamine (Regitine)
Silodosin (Rapaflo)
Doxazosin (Cardura)
Metoprolol (Toprol XL)
45
A proportionality constant that relates the total drug in the body to the plasma concentration of the drug. (3-31)
clearance
volume of distribution
bioavailability
46
A prodrug is what type of metabolite? (3-40)
altered activity
bioactive
similar activity
inactive
47
Which type of receptor cell is pre-synaptic? (5-13/16)
b1
b2
a1
a2
48
Where in the GI tract would ibuprofen be more likely to ionize? (3-10/11)
large intestine
stomach
small intestine
esophagus
49
Normal cells secrete these local chemicals that are rapidly destroyed. Do not enter blood or travel in the body.(4-5)
local mediators
neurotransmitters
hormones
50
Which of the following is a leading cause of injury and avoidable harm in health care systems? (1-28)
idiosyncratic reaction
medication error
adverse drug reaction
adverse drug event
51
You prescribe a pt a prodrug and you find out they are also ingesting an inducer, what would you expect to see? (3-45)
therapeutic failure levels
no change
decreased rate of active metabolite
toxicity levels
52
How would you monitor a patient on phenylephrine? (5-34)
ECG
temperature
blood pressure
heart rate
53
Which of the below is most likely to cause metabolic acidosis? (6-26)
Dexmedetomidine (Precedex)
Ketamine (Ketalar)
Propofol (Diprivan)
Opioids
54
Succinylcholine (Quelicin) should be utilized for procedures lasting how long? (6-35)
<3 mins
<10 mins
<240 mins
<60 mins
55
Which best describes FDA pregnancy category X? (1-43)
studies have failed to demonstrate risk during the 1st trimester
positive evidence of human fetal risk, risk clearly outweighs the benfits
positive evidence of human fetal risk, benefits may outweigh the risk
animal reproductive studies failed to demonstrate a risk to the fetus
56
Which is not a possible result of an anticholinergic drug? (4-35)
increased peristalsis
facial vasodilation
confusion
cycloplegia
57
What is the max quantity of a schedule II prescription under federal law? (1-36)
30
45
none
90
58
Which drug is primarily used to treat irritable bowel syndrome? (4-49)
Oxybutynin (Ditropan)
Benztropine (Cogentin)
Scopolamine (Transderm Scop)
Dicyclomine (Bentyl)
59
What is the last part of the body to become paralyzed during the use of neuromuscular blocking agents? (6-33)
face/eyes
diaphragm
fingers/toes
intercostal muscles
60
Whhich is not an adverse effect you would expect with Dopamine (Intropin)? (5-25)
hyperglycemia
tachycardia
tissue necrosis
anxiety
61
Highly water soluble drugs are more likely to cross the blood brain barrier. (3-34)
True
False
62
Which of the following is true regarding first-pass metabolism? (3-36)
liver is secondary site
may limit drug efficacy is clearance is high
mainly regarding oral administration
increases bioavailability
63
What best describes the result of a synthetic reaction? (3-39)
polar metabolite
always inactive
water soluble
covalent compound
64
What medication is a convulsant antidote for nerve agents? (4-41)
Diazepam
Pralidoxime
Echothiophate
Atropine
65
Which is considered part of the peripheral compartments in the two compartment model? (3-29)
plasma
lung
CSF
heart
66
In early pregnancy, teratogenic agents may induce what? (1-42)
physiologic defects
fetal alcohol syndrome
structural abnormalities
mental retardation
67
Which of the below is not a factor when determining control of schedules? (1-33)
scientific knowledge
relative potential of abuse
chemical makeup
dependence liability
68
What affect might you see with someone on monoamine oxidase inhibitors if they are given Norepinephrine(Levophed)?(5-21)
norepinephrine toxicity
monoamine oxidase inhibitor toxicity
monoamine oxidase inhibitor below therapeutic effective level
norepinephrine below therapeutic effective level
69
What route of administration of Ketamine (Ketalar) most likely to cause respiratory depression? (6-24)
PO
IV
IN
IM
70
Which of the below can result in either bradycardia or tachycardia? (6-26)
Ketamine (Ketalar)
Propofol (Diprivan)
Dexmedetomidine (Precedex)
Opioids
71
Who determines is a drug should be Rx or OTC? (1-6)
FDA
DEA
Pharmacist
PA
72
What category of alteration in drug metabolism can Stevens-Johnson Syndrome fall into with carbamazepine? (3-47)
age
concurrent disease
genetic variability
nutrition
73
Acetylcholine has action at what receptors? (4-6)
pre-synaptic nicotinic
post-synaptic muscarinic
pre-synaptic muscarinic
post-synaptic nicotinic
74
Off-label uses for drugs are approved by the FDA as safe and effective. (1-7)
True
False
75
Ibuprofen will ionize and cross membranes to be absorbed in the stomach. (3-14)
False
True
76
All of the below are factors that encourage noncompliance except which? (1-18)
side effects
frequency of dosing
difficult to follow directions
symptomatic diseases
77
How many refills are allowed on schedule III drugs? (1-15)
0
11 within 12 months
1
5 within 6 months
78
Which item is not mandatory under patient information on a prescription? (1-12)
full name
date of birth
address
phone number
79
What is most important about the effects of Pralidoxime (2-PAM, Protopam)? (4-41)
relieves muscarinic signs such as salication
muscular weakness when given parentally
prevents of abolishes bradycardia
reverses paralysis of respiratory muscles
80
You give a postpartum patient Bathanechol (Urecholine). What result are you trying to elicit? (4-21)
increased aqueous humor outflow
salivation
detrusor muscle contraction and trigone sphincter relaxation
decreased peristalsis
81
Esmolol (Brevibloc) is what type of B Adrenergic blocking agent? (5-66/67)
non-selective
b1 selective
mixed a1 and non-specific
intrinsic sympathomimetic activity
82
How much can you order as refills on Dextroamphetamine (Dexedrine) for treatment of ADHD? (5-44)
no refills
11 refills
5 refills
1 refills
83
For someone with Child-Pugh class A, how would you instruct them to take metronidazole? (3-48)
take 200% dose
no change
take 50% dose
84
Alkalinizing the urine wwill increase the elimination of an acidic drug. (3-17)
False
True
85
What drug regulation requires government pre-approval of drugs? (1-46)
1906 Food and Drug act
1966 Fair Packaging and Labeling Act
1938 Food, Drug, and Cosmetic Act
1914 Harrison Tax Act
86
Raynaud's Disease can be improved by what type of adrenergic antagonist?
a1-blocker
nonspecific b-blocker
a1a-blocker
b1-blocker
87
Which of the following is acceptable on a prescription? (1-25)
0.5 mg
2.0 mg
Q.D.
c.c.
88
What medication might you prescribe for treatment of PTSD? (5-59)
Doxazosin (Cardura)
Terazosin (Hytrin)
Alfuzosin (Uroxatral)
Prazosin (Minipress)
89
What form is used for a written DoD prescription? (1-12)
DD Form 1892
DD Form 1289
DD Form 1298
DD Form 1928
90
What drug do you suspect if a patient has these symptoms: bradycardia, weight loss, and erectile disfunction?(5-66)
Tamsulosin (Flomax)
Ephedrine (Pretz-D)
Prazosin (Minipress)
Bisoprolol (Zebeta)
91
What drug regulation was created in response to fatal poisoning, requiring drugs be shown safe before marketing? (1-46)
1914 Harrison Tax Act
1906 Food and Drug act
1938 Food, Drug, and Cosmetic Act
1966 Fair Packaging and Labeling Act
92
Pt at to ER with bronchoconstriction and miosis, unsure of what medication. What do you think is most likely? (4-12/10)
parasympatholytics
cholinomimetics
antimuscarinics
93
What are the FDA required subsections in the labeling titled? (1-44)
pregnancy
postpartum
females and males of reproductive health
lactation
94
Schedule I drugs are eligible for 1 refill. (1-15)
False
True
95
Which route of transmission has approximately the same limited bioavailability as oral? (3-24)
rectal
transdermal
inhalation
sublingual