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SAM FINAL (Hepatobiliary) Flashcards | StudBud
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SAM FINAL (Hepatobiliary)
SAM FINAL (Hepatobiliary)
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1
Platynosum fastosum (liver fluke) in cats can cause either enzymes pattern. After diagnosing on fecal, how do you treat?
Surgical if obstructed, otherwise Permethrin
Ivermectin
Surgical if obstructed, otherwise Praziquantel
Fenbendazole
2
What would cause a Liver FUNCTION failure? (Increased: BUN & TBILI Decreased: GLU, ALB, CHOL)
Portosystemic shunt, Feline hepatic lipidosis, End-stage liver disease
Leptospirosis, Biliary neoplasia, Biliary disease
Salmonella, Pancreatitis, Bordetella
Toxins, Infection, Endocrine disorders
3
The gallbladder contains bile which instantly causes peritonitis if it leaks. How is this prevented?
Pack saline-soaked sponges between liver and xiphoid + Antibiotics
Complete ligation of the hepatobiliary triad
Systemic steroids prior to anesthetizing
Place a cholecystostomy tube prior to procedure
4
If the liver isn't working, has a shunt, or is in end-stage failure (cirrhosis= acquired shunts) a patient can get:
Pancreatitis
Cholangitis
Hepatic encephalopathy
Hepatic lipidosis
5
The portal system & arterial system supply the liver with blood. Where does the arterial system branch from?
The hepatic artery
The portal artery
The portal vein
The hepatic vein
6
Which of the following are common primary hepatic/ biliary neoplasias in dogs?
Hepatocellular carcinoma, adenoma, & Histiocytic sarcoma
Biliary cystadenoma, Lymphoma, & Mast Cell Tumor
Angiosarcoma, Blastoma, Hemangiosarcoma
Biliary adenoma, Biliary sarcoma, B cell neoplasia
7
Which breed is predisposed for Copper hepatopathy & Lobular dissecting hepatitis?
Labrador Retriever
Doberman
English Cocker Spaniel
Bedlington Terrier
8
What position should the patient be in for hepatic surgery?
Left lateral
Reverse Trendelenburg
Trendelenburg
Right lateral
9
What might cause the following results?
Pancreatitis, Hyperadrenocorticism, Non-specific liver fibrosis
Pancreatitis, Bordetella, Salmonella, Shock
Portosystemic shunts, End-stage liver, Shock
Pancreatitis, Shock, Systemic inflammation, Trauma, Endocrine disorder
10
An outdoor cat from Texas suddenly becomes very ill with a hepatocellular pattern. What is the MOST likely Ddx?
Leishmania
Babesia
Bartonella
Cytauxzoon
11
What is the only vein that SHOULD exist between the renal & hepatic veins?
Gastroduodenal vein
Portal vein
Phrenicoabdominal vein
Cranial mesenteric vein
12
A dog presents smaller than their littermates. Urinalysis (ALWAYS do!) shows ammonium biurate crystalluria. What next?
Protein-C
Bile acids
CT with angiography
Ammonia
13
Prior to hepatic surgery (FNA, Biopsy), what tests NEED to be performed?
Bile acids, Ammonia, HCT
CBC, Chem, Urinalysis
T4, Chem, Urinalysis
PCV, Coagulation profile, Blood type
14
Most hepatic neoplasia is metastatic. Diagnosis is achieved with:
Biopsy & CBC/ Chem
Abdominal radiographs & CBC/ Chem
Urinalysis, CBC, Chem, Scintigraphy
Chest radiographs, Abdominal ultrasound, & Biopsy
15
Which of the following treatments requires a diagnosis for use (cannot be used empirically)?
D-penicillamine
Colchicine
Cholestyramine
Ursodiol
16
Of the following routes of surgical attenuation (TOC for shunts) which is only an option for Intrahepatic Shunts?
Ameroid Constrictor
Self-retaining Polyacrylic Acid-Silicone
Thin Film Bands
Percutaneous Transjugular Coil Embolization
17
Copper hepatopathy is genetic for Labrador retrievers, Bedlington terriers, & Doberman. How is is treated?
Chelation for 6 months (D-penicillamine & Trientene) + SAM-e
Anti-inflammatory prednisone + High copper diet
Ursodiol + Hypertonic saline IV
Low zinc diet + NSAIDs
18
Which diagnostic test is 100% sensitive and is the BEST for assessing vascular liver disease early on?
Protein C
Chem + CBC
Ammonia
Bile acids
19
A dog with end-stage liver disease presents with ascites due to low albuminemia & cirrhosis. What is their MST?
6 months - 2 years
4 weeks
5 months
2 months
20
Which antibiotics are excreted in active form in the bile?
Penicillin, Amikacin, Florfenicol
Amoxicillin, Cephazolin, Enrofloxacin
Ceftiofur, Tetracycline, Metronidazole
Gentamicin, Erythromycin, Ampicillin
21
To surgically identify a PSS (thin-wall & turbulent) you approach ventral midline. Where is the portal vein located?
Between the renal and hepatic veins
At the greater and lesser curvatures of the stomach
Within the epiploic foramen
22
Feline Infectious Peritonitis dry form can mimic chronic liver disease. How can you obtain a definitive diagnosis?
Transtracheal wash & cytology
FNA of liver
Feline covid titer
Biopsy or Immunochemistry
23
For a dog with an inflammatory hepatopathy, which of the following are NEGATIVE prognostic factors?
Ascites, Prolonged coagulation, Hyperglobulinemia
Hypoglobulinemia, Hyperproteinemia, Thrombocytosis
Blood pressure, PU/PD, Hypophagia
Age, Breed, BUN levels
24
ALT & ALKP are Liver enzymes that shift with Liver damage. What changes do you expect with Liver FUNCTION failure?
Increase BUN & TBILI Decrease GLU, CHOL, ALB
Increase BUN, TBILI, ALB Decrease GLOB
Increase GLU, CHOL, ALB Decrease BUN & TBILI
Increase GLOB Decrease BUN, TBILI, ALB
25
The liver is the largest gland in the body. For surgery, which area is the hardest to reach & carries worst mortality?
Central division
Right division
Left division
26
What is the emergency treatment for a cat with hepatic lipidosis (diagnosed with FNA)?
Check BG, Levetiracetum, Lactulose, Antibiotics
Check Potassium, Diazepam, High protein diet
IV fluids, High protein diet, Silimarin
IV fluids, Blood transfusion, Calcium gluconate
27
Which treatment below can be used empirically, but carries the risk of side-effects?
NSAIDs
Cholestyramine
Ursodiol
Silymarin
28
Although a markedly high ALT (thousands) suggests liver toxicity, what provides a definitive diagnosis?
Ammonia
Bile acids
Ultrasound
History or Biopsy
29
Non-obstructive biliary disease can progress to be obstructive. What is monitored in hospital to catch this?
Ultrasound, Ammonia, Bile Acids, ALT
Bile Acids, ALT, GLU, CHOL
Ultrasound, TBILI, ALKP, GGT
Ammonia, GGT, ALT, BUN
30
Which of the following results from an abdominocentesis warrants emergency surgery?
WBC & lipids
Colorless fluid with lack of neutrophils
Bile pigment & neutrophils
Red coloration & lack of thrombocytes
31
Which diagnostic test can BEST differentiate Portosystemic Shunt from Microvascular Dysplasia?
Protein C
Blood Glucose
Bile Acids
Ammonia
32
The Pringle Maneuver can be placed for a maximum of 20min. This is used to block which structures?
Common hepatic duct, Hepatic portal vein, Proper hepatic artery
Caudal vena cava, Hepatic portal vein, Hepatic artery
Common hepatic duct, Hepatic vein, Hepatic portal artery
Caudal vena cava, Right lateral lobe, Renal artery
33
What medications prevent further damage from cholestasis?
Aminoglycosides + Amoxicillin
Ursodiol + Silymarin or SAM-e
High dose Midazolam + Calcium gluconate
Fenbendazole + Levetiracetum
34
Which of the following radiographic findings support the diagnosis of portosystemic shunt?
Microhepatica + Renomegaly
Hepatomegaly + Kidney atrophy
Microhepatica + Kidney atrophy
Hepatomegaly + Renomegaly
35
Which infectious diseases will show a cholestatic pattern (high ALKP)?
Neoplasia
Leptospirosis & Ascending infection (Salmonella, E. coli)
Pasteurella & Histophilus
Focal abscessation
36
What is the treatment for toxic injury to the liver?
Calcium gluconate (IV), Lipid emulsion, Crystalloids (IV)
N-acetylcystine (IV), Silymarin, Cholestyramine, SAM-e (PO)
High calorie diet, Doxycycline, Amikacin
NSAIDs, Heparin (IV), High fat diet
37
When is a "liver diet" indicated?
Copper hepatopathy, Hepatic encephalopathy
Cholangitis, Hepatitis
Hepatic lipidosis, Gallbladder disease
Triaditis in cats, Pancreatitis
38
Toxins can cause hepatocellular damage leading to necrosis. Sometimes this occurs weeks after exposure like with:
Xylitol
Heavy metals
Sago palm
Blue-green algae
39
Cats with inflammatory cholangitis commonly have secondary bacterial cholangitis. This is diagnosed via:
Cholecystocentesis with culture & cytology
Blood culture
CBC/ Chem/ UA
Biopsy
40
A dog presents with respiratory, ocular, and CNS symptoms. Bloodwork shows a hepatocellular pattern. Mot likely Ddx?
Canine adenovirus 1
Leptospirosis
Canine parvovirus
Bordetella
41
What is a good empiric therapy plan for a hospitalized patient pending results on an infectious hepatopathy?
IV sulbactam, IV enrofloxacin
IV cefazolin, IV rifamycin
PO doxycycline, IV trimethoprim, PO tetracycline
IV ampicillin, IV metronidazole, IV fluoroquinolone
42
Which breeds are predisposed for gallbladder mucoceles (average around 11 years old)?
Dachshunds, German shepherds, Dalmatians, Chihuahua
Shetland sheepdog, Black labs, Yorkie terriers, Huskies
Mini schnauzers, Shetland sheepdog, Chihuahua, Pomeranian
Golden retrievers, Mini schnauzers, Poodles, Australian shepherds
43
The half-life of ALT in species is different. In which species is even a mild increase clinically relevant?
Cat
Dog
Ferret
44
Cats have a different pathophysiology for cholangitis than dogs. How do cats obtain cholangitis?
Descending from hematogenous spread of infection to the Liver usually
Ascending from GIT usually, sometimes from primary liver disease
Usually secondary to primary liver or gallbladder disease
Usually from portosystemic shunting
45
How can Salmonella be diagnosed if exposure is suspected?
Fecal culture
FNA
Abdominal ultrasound
Fecal PCR
46
What are the indications for a biliary stent, cholecystostomy tube, or bile duct stent?
Reversible situations when patency is demonstrated but functional obstruct
When there is a mucocele
When permanent stenting is needed due to mechanical obstruction
For cases where bile peritonitis is anticipated
47
What is the medical management for a patient with hepatic encephalopathy or a porto-systemic shunt?
Antibiotics, Low protein diet for life, Proton Pump Inhibitor, SAM-e
Transition to vegetable proteins + Lifelong NSAID treatment
EG tube for feedings of high calorie slurry
Probiotics, High protein diet for life, Cholecalciferol
48
Hepatobiliary surgery is considered what type of surgery?
Clean-contaminated
Contaminated
Dirty
Clean
49
Of the possible palliative treatments below for end-stage liver disease, which one helps reduce pressure from cirrhosis?
Plasma infusion
Spironolactone
Low protein diet
Ursodiol
50
A cat with gallbladder disease needs what kind of diet?
"liver diet"
Ultra low fat
Novel protein/ hypoallergenic
Ultra high calorie
51
Inflammatory liver diseases (i.e. copper hepatopathy, breed hepatopathy, infectious, toxic, idiopathic) are diagnosed:
Via FNA
Via Biopsy
Via Cytology
Via Culture
52
Which of the following are common causes of acute hepatic failure (>75% of hepatocytes lost)?
Infection, Diet, Pancreatitis
Metabolic, Trauma, Infectious, Vascular, Lyme Disease
Comb's, Respiratory illness, Metabolic, Neoplasia
Toxins, Leptospirosis, Neoplasia, Feline hepatic lipidosis
53
What might cause the following results?
Leptospirosis, Biliary neoplasia, Portosystemic shunts
Pancreatitis, Hyperadrenocorticism, Non-specific liver fibrosis
End-stage liver disease, Porto-systemic shunts, Hypoadrenocorticism
Pancreatitis, Shock, Systemic Inflammation, Trauma, Endocrine disorder
54
What breed has the genetic form of vacuolar hepatopathy? Monitor for development of hepatocellular carcinoma.
Chihuahua
Yorkshire terrier
Miniature schnauzer
Scottish terrier
55
What type of congenital (individual) Porto-Systemic Shunts do medium to large breed dogs tend to get?
Extrahepatic (Portal vein hypoplasia) PSS
Intrahepatic (Persistent ductus venosus) PSS
56
Ultrasound reveals a small liver. This may be due to:
Chronic inflammation or Liver failure
Acute liver damage or Vascular liver issue (shunt)
Vascular liver issue (shunt) or Chronic inflammation
Toxicity or Acute liver damage
57
ALT is primarily hepatocellular, ALKP is primarily cholestatic. What does the following results suggest?
Mixed, higher hepatocellular
Primarily hepatocellular
Mixed, equal
Mixed, high cholestatic
58
After a CHEM panel, you can confirm Liver FUNCTION failure with Ammonia, PT/PTT, and:
Abdominal Ultrasound
Abdominal Radiographs
Bile Acids
Urinalysis