SI #4 : Jackson & Jois Diuretics and Vasodilators

True or False: when nitroprusside solutions are exposed to light, they turn from a green/blue to red/brown color.

A hallmark sign of ischemic heart disease on an EKG is an inverted t-wave.

What is the following group called?

Which of the following groups lowers the activity of this drug?

Where does the majority of reabsorption happen in the Nephron?

Which of the following is false?

Osmotic diuretics primarily work in the ________________.

Which of the following describes angina that results from insufficient blood flow due to atherosclerosis?

The distal convoluted tubule & collecting duct are impermeable to water unless _____________ is present

Nitroglycerin can be taken with phosphodiesterase inhibitors.

Ranolazine inhibits late Na channels, this shortens ______________ of the cardiac contractile cell action potential.

What changes does Spironolactone need to prevent it from binding to hormone receptors?

Which of the following disease states does not cause excessive demand on the myocardial muscle?

Which of the following groups changes Aldosterone from an agonist to antagonist?

Ischemic heart disease results from insufficient blood supply and/ or increased O₂ demand in the myocardial muscle.

Which of the following is false?

Calcium channel blockers can be used for long-term angina prophlaxis

An overdose of nitroglycerin can lead to cyanide poisoning.

Ivabradine decreases __________ to decrease oxygen demand.

How is the release of cyanide caused?

What are the two reactions that occur to hydralazine?

Which of the following are potassium-sparing diuretics? (SELECT ALL THAT APPLY)

What enzyme catalyzes the reaction below, and where does the reaction take place?

Loop inhibitors inhibit the Na+/K+/Cl symporter in the ascending loop of Henle & work to attenuate the TGF mechanism.

Which of the following is false?

True or False: Osmotic diuretics require no metabolism and cause all electrolytes to freely flow into urine.

How do fast acetylators hydralazine dose need to be adjusted, compared to a normal acetylator?

The major MOA of organic nitrate is to .....

Furosemide, a loop diuretic, has what quality to make it a good diuretic drug?

Carbonic anhydrase inhibitors have the potential to cause metabolic alkalosis.

Based on the following structures, which binds with the highest affinity to carbonic anhydrase?