MOCK QUIZ BOWL APRIL 26

NOT a cardinal sign/symptom of peritonitis

Which of the following are thrombopoietin-receptor agonists are given as treatment for patients with Chronic ITP?

What is the agent of choice in Ethylene Glycol Intoxication?

Major risk factors for OSAHS include

The presence of which of the following argues against the diagnosis of IBS?

most common location for colonic ischemia and is situated where collateral vessels meet at the splenic flexure

Which of the following is a class I indication for AVR in patients with severe AR?

associated with hypercoagulable states such as inherited thrombophilia’s, polycythemia vera, and carcinoma

What is the most common cause of chronic hypercalcemia?

The ideal lung donor, except:

What is the most common cause of primary adrenal insufficiency worldwide?

In septic shock, the primary physiological mechanism leading to increased cardiac output despite hypotension?

The QT interval on an electrocardiogram represents which phase of the cardiac cycle?

A patient with a large PDA and secondary pulmonary hypertension with right-to-left shunting at the great vessel may show

Which of the following is a cause of high output heart failure?

Neural Crest cells are sensitive to this vitamin, a deficiency of which can cause aortic arch abnormalities.

This short acting CCB when given during AMI may be associated with increased risk of mortality

Best predictor for  long-term prognosis for colorectal cancer?

Electrical alternans syndrome. 

TRUE regarding the occurrence of liver injury in idiosyncratic drug reactions

What was the key finding regarding intensive blood glucose control (targeting 81–108 mg/dL) in the NICE-SUGAR trial?

Signs of PH evident on Chest Radiograph are the following except:

Bacteria associated with colorectal cancer?

Which lipid parameter is the primary target of therapy according to the 2023 ACC/AHA guidelines?

Most frequent visceral site of colon cancer metastasis?

What was the COURAGE trial's key finding regarding PCI?

most likely etiology for nausea, vomiting, crampy abdominal pain and diarrhea 4 hours after intake of mayonnaise

The following typically presents with acute inflammatory monoarthritis EXCEPT

40M with no comorbidities but with severe MS and atrial fibrillation, which of the following is appropriate?

Principal iron regulatory hormone

Which of the following is the most characteristic finding in PFTs of a patient with idiopathic pulmonary fibrosis

Which of the following predicts increased risk of exacerbations in asthma?

Screening recommendations for asymptomatic average risk subjects, which is the correct screening recommendation?

most appropriate initial test for a patient presenting with massive bleeding suspected to be from the small intestine

Which of the following clinical findings is more indicative of an upper gastrointestinal cause of bleeding?

Atypical causative organism of pneumonia EXCEPT:

Which of the following is considered as the most consistent clinical feature in IBS?

Which of the following electrolyte abnormalities can cause nephrogenic DI?

Most effective chemopreventive agent for primary prevention of colorectal cancer?

What was the main conclusion of the CAST trial?

Apnea – Hypopnea Index 5 events/hour

In the PARADIGM-HF, What was the primary outcome that sacubitril-valsartan significantly reduced?

Which of the following is the most likely biochemical finding in a patient with a pheochromocytoma?

tests the concentration of chloride in sweat, a vital component and gold standard in diagnosing cystic fibrosis

Second most common type of exudative pleural effusion

In a patient with suspected adrenal insufficiency, which laboratory test is considered the most sensitive for diagnosis?

In metabolic acidosis of Chronic Kidney Disease, the goal is to maintain the [HCO₃-] to a value of at least?

Which of the following drugs can cause gout?

In a patient with rheumatic fever, which of the following cardiac valves is most commonly affected?

Hyperkalemia in volume depletion is due to:

site commonly spared by diverticular disease

In Brugada syndrome, which of the following is the most likely underlying genetic mutation?

60/M cirrhotic from chronic HBV infection. What is the recommended method of surveillance for hepatocellular carcinoma?

What are the pathophysiologic abnormalities that can be observed in this patient except?

Infectious agent associated with Gastric MALT lymphoma

asthma trigger that increase in airway osmolality leading to activation of mast cells to release inflammatory mediators

In Takotsubo cardiomyopathy, which of the following is the most likely triggering factor?

What is the preferred treatment for patients with 1,25 (OH)₂ D-mediated hypercalcemia?

What is the most common cause of acute pancreatitis?

Which of the following tests the intrinsic and common pathways of secondary coagulation?

In hypertrophic cardiomyopathy (HCM), mutations in which sarcomeric protein gene are most frequently identified?

enzyme causing pancreatic acinar cell injury and inflammatory cascade during acute pancreatitis

Which of the following is TRUE regarding the activation of neurohormonal systems in heart failure?

accounts for > 50% of fulminant cases of viral hepatitis

72M with confusion, ataxia, and ophthalmoplegia. His history reveals alcohol use disorder. Which is most appropriate?

first-line treatment for Graves' disease in a non-pregnant adult according to the latest ATA guidelines

Minimum number of lymph nodes sampled necessary to adequately define pathologic stage?

LEAST helpful for constipation-predominant irritable bowel syndrome

Hallmark of group 2 pulmonary hypertension

Which of the following DOES NOT characterizes dyspnea typical of COPD patients?

NOT a benefit of high-dose constant-infusion PPI among patients with GI bleeding from PUD

Which of the following factors can activate Factors I, V, VII, VIII, XI, XIII, protein C, and platelets?

Correct of FDA approved therapies for treatment of Pulmonary Arterial Hypertension

Major side effect from irinotecan?

predict the effect of ICS on top of bronchodilator use in the preventing future exacerbations

Which of the following is NOT an identified risk factor for H. pylori colonization and possibly infection?

Which of the following is most closely associated with a high SYNTAX score?

Rigid bronchoscopy is highly recommended in?

Sacroiliitis is a sine qua non sign of Seronegative Spondyloarthropathy which include the following EXCEPT?

Which of the following statements best describes secondary hemostasis?

“Starry sky” appearance is found in?

Which of the following infectious agents may also cause ulcer disease?

What is the most common form of acute unilateral urinary obstruction?

Hypercalcemia due to excessive PTH production is seen in the following condition/s:

 antibiotic posing the LEAST risk of C. difficile infection

Which genetic mutation is most strongly associated with familial medullary thyroid carcinoma as part of MEN type 2A?

Which of the following is the immediate response of a blood vessel to injury?

What is the principal cause of atrial fibrillation in patients with mitral stenosis?

The ff are sustained genetic ventricular arrhythmias except

A restrictive deficit ILD is typified by

YMDD mutations in the HBV polymerase motif renders resistance to this antiviral drug against Hepatitis B.

Screening recommendation for colorectal cancer?

Which of the following is the recommended next diagnostic modality for the patient?

What thoracic surgical procedure should you perform to create a Clagette window for bronchopleural fistula with empyema?

In CAH due to 21-hydroxylase deficiency, which of the following findings is most commonly seen?

Which of the following conditions is closely associated with gastroesophageal reflux disease?

supraventricular tachyarrhythmias presenting as an irregularly irregular rhythm with a narrow QRS on ECG

If PF ADA is elevated, what is the recommended duration of anti TB treatment?

Which is true regarding pathophysiology of pneumonia:

Which of the following is the most common cause of acute gastritis?

Silica, aluminum, and iron deposit in higher areas of the tracheobronchial tree. What is the size of these particles?

Inflammation of the ligamentous attachment onto the bones is called enthesitis an example of which is the following?

Most common cause of chylothorax

One ml of red cell is equivalent to how many mg of elemental iron?

In the management of bronchial asthma, the goals of therapy includes which of the following?

In patients with asymptomatic AS Vmax 4m/s and stage C (EF of 40%), best treatment to prevent mortality

examples of vagal maneuvers used for the termination or slowing of supraventricular tachycardia, EXCEPT:

This structure is composed of a single layer of endothelial cells continuous with capillaries.

What was the major advantage of ticagrelor demonstrated in the PLATO trial?

The term used for involvement of 2-4   joints commonly presented by reactive arthritis:

MRI of the breast would be recommended as a screening modality  in the following women, EXCEPT:

Which of the following endoscopic findings require a biopsy due to increased risk of being malignant?

Which of the following was the primary composite outcome reduced by intensive treatment in the SPRINT trial?

Most common clinical presentation of Hemophilia A

Which of the following is true regarding the DIG trial which evaluated the role of Digoxin in heart failure?

Which of the following mutations is present in patients with Essential Thrombocythemia?

Transudative Pleural effusion

This fluid should be avoided as resuscitation fluid because it increases risk of developing severe acute kidney injury.

Which genetic mutation is most commonly associated with dilated cardiomyopathy (DCM)?

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is most commonly associated with mutations in which gene?

patients with PUD who DO NOT require endoscopic therapy and may receive only standard doses of proton pump inhibitors

This is the most common complaint in patients presenting with interstitial lung disease:

Which of the following can cause acute mitral regurgitation?

Which of the following is a risk factor for early deterioration in CAP?

lobar PNA phase characterized by predominance of macrophage, debris already cleared and inflammatory response resolved

Which of the following tests the extrinsic and common pathways of secondary coagulation?

Which of the following medications can cause hypercalcemia?

The duration of symptoms that is considered chronic is

Most common type of anemia

rare gastropathy characterized by large, tortuous mucosal folds most prominent in the body and fundus sparing the antrum

Which of the following conditions is characterized by mutations in the NOTCH1 gene leading to aortic valve disease?

According to 2024 ADA, the medication preferred for patients with type 2 diabetes and established ASCVD

A deficiency in this enzyme is most strongly linked to the pathogenesis of chronic granulomatous disease?

Which of the following factor is deficient in Hemophilia A?

Which of the following best describes lower gastrointestinal bleeding caused by diverticular disease?

Which of the following drugs produces predictable and dose-related hepatic injury?

Which of the following accounts for most cases of dyspepsia among the general population?

In chronic thromboembolic disease, what is the primary mechanism of elevated pulmonary artery pressures?

In hypertrophic cardiomyopathy, which of the following findings is most commonly associated with sudden cardiac death?

Which of the following is the key pathophysiological mechanism underlying hypertrophic obstructive cardiomyopathy?

Which of the following is the best way to initially assess a patient with gastrointestinal bleeding?

Which of the following factors is most critical for determining the prognosis of a patient with acute aortic dissection?

Accelerated Idioventricular rhythm except; 

Which of the following organisms has been used to treat IBD?

In the RE-LY trial, what advantage did dabigatran demonstrate over warfarin in atrial fibrillation?

cytokine with the most prominent role in the pathogenesis of RA by promoting synovial inflammation and joint damage?

Hinchey classification for a perforated diverticulitis that has closed spontaneously but with distant abscess formation

potent antiretroviral agent highly active against both wild-type and lamivudine-resistant HBV

Which metabolic disturbance is most strongly associated with the development of nonalcoholic steatohepatitis (NASH)?

Site of iron absorption

A patient with acute hepatitis should undergo which serologic tests for initial screening?

Treatment for primary myelofibrosis patients with massive splenomegaly

Polyp with the highest probability of becoming malignant?

Which of the following mechanisms underlies the pathophysiology of exercise-induced bronchoconstriction in asthma?

Correct of categories of PH EXCEPT:

First available prostanoid for PAH delivered as a continuous IV infusion and improves functional capacity & survival

most seen in COPD patients categorized as GOLD Stage IV

The following are considered TRUE regarding treatment for cryptogenic organizing pneumonia, EXCEPT:

In patients with asymptomatic AS Vmax 4m/s and stage C (EF of 40%), best treatment to prevent mortality

Gold standard for diagnosis and assessment of disease severity of PH

A  26/M finished a distance of 21K run in 2 hrs, took only few sips of water and a power drink. Expected body response?

Which of the following choices is a cause of pre-hepatic portal hypertension?

diastolic murmur heard best in the 3rd ICS along the left sternal border intensified by strenuous and sustained handgrip

The FLAME study compared indacaterol/glycopyrronium to salmeterol/fluticasone in COPD. What was the primary finding?

Causes of LQTS and Torsade’s except:

In Eisenmenger syndrome, which of the following is the primary physiological process responsible for cyanosis?

NOT a common cause small-intestinal gastrointestinal bleeding among patients above the age of 40 years

colorectal cancer prevention strategy for patients with long-standing ulcerative pancolitis or Crohn’s colitis

Which of the following aminotransferase pattern is interpreted correctly?

72M with confusion, ataxia, and ophthalmoplegia. His history reveals alcohol use disorder. Which is most appropriate?

Which of the following causes most cases of upper gastrointestinal bleeding?

1.Which laboratory parameter increases the likelihood of a cholestasis?

Which of the following is the most accurate diagnostic test for acromegaly?

Which of the following is TRUE regarding cor pulmonale?

In normal individuals, FEV1 reaches a lifetime peak at which age?

The following is compatible with an articular source of pain:

In a patient with ARDS, which ventilatory strategy has been shown to improve survival?

A patient with chronic hepatitis should undergo which serologic tests for initial screening?

Causes of hypocalcemia, EXCEPT:

Criteria for complete remission for acute leukemia patients given induction chemotherapy:

Mitral valve prolapse is most commonly associated with what valvular abnormality?

NOT included in the Rome IV diagnostic criteria for irritable bowel syndrome

Which of the following statements best describes primary hemostasis?

Which of the following is the most characteristic electrocardiographic finding in pericarditis?

Transudative Pleural effusion

a patient with splenomegaly, fatigue, weight loss, and PBS with teardrop-shaped cells, NRBCs, myelocytes, metamyelocytes

Genetic abnormalities in the PKP2 gene encoding plakophilin-2 are most strongly linked to which cardiac syndrome?

Most common clinical presentation of severe form of Hemophilia A

Mutations in the FBN1 gene are characteristic of which genetic syndrome associated with cardiac abnormalities?

metabolic abnormality NOT associated with ileus

In long QT syndrome, ion channel mutation most frequently implicated in inherited forms of the disease

Treatment of idiopathic arrhythmias except; 

an example of the a long-acting Beta agonist

The airway may collapse at different sites EXCEPT:

has the least propensity to develop massive hepatic necrosis

The hallmark of primary hyperparathyroidism includes which of the following biochemical abnormalities?

associated with mutations in genes encoding sarcoplasmic reticulum calcium-handling proteins such as CASQ2 and RYR2

Standard medical therapy with highest level of evidence for efficacy.

NOT a function of the endothelial cell within the blood vessels

What bacterial growth should raise concern for infection, even in the setting of poor sputum samples?