Blood Chemistry

Choose all of the follwoing facts about the COX pathways that are correct.

PT tests the extrinsic pathway and aPTT tests the intrinsic and common pathway.

Platelets are made in the bone marrow

What is the absolute energy source for a RBC?

Which of the follwoing are antithrombotic factors and have their function correctly paired?

Pernicious anemia is caused by a deficiency of Vitamin K.

Transport of absorbed lipids in the blood requires the binding of an amphipathic protein.

Essential fatty acids cannot be constructed within our own body. Which of the following are essential fatty acids?

***What is the normal total plasma protein concentration?***

RBCs are broken down into globin and heme. Heme is then broken down into which two subtnaces?

Biliverdin is the product that results form oxidative clevage of the porphyrin ring.

In the extrinsic pathway, factor ___ is activated by ______ to start the cascade of events.

Which cell type has an absolute requirement for glucose?

Acetyl CoA is the source of carbons found in all fatty acids.

Which of the following are involved in the formation of a clot when vascular tissue is injured?

Eicosanoids is a group of compounds that include prostacyclin, prostaglandins, leukotrines, lipoxins, and thromboxanes.

Match the following muscle types with their characteristics.

Which factor is the most essential regulator of RBC production?

What is another term for platelets?

Which two molecules form urea in the liver during the Ornithine cycle?

What components of the platelt play a function in clot formation?

Albumin is the most abundant plasma protein and is produced in the spleen.

What are the two main functions of albumin?

Which substance is the main fibrinolytic agent involved in the breakdown of clots?

Which of the following would lead to a hyperpolarization of the membrane?

Select pathologic hemoglobin conditions that are properly matched with their definitions.

Which of the following would result in a depolarization of the membrane?

Blood is made up of water, proteins and cells. Which of the following %'s represents the cellular fraction of blood?

What are the three stages of hemostasis?

Injured endothelium produces antithrombotic factors.

The common pathway is where both pathways meet, starting with activation of factor ___ and ends with formation of a___?

Glucose is taken up by the cells and is trapped as glucose-6-phosphate. What are the potential fates of G-6-P?

In regards to fatty acids, the shorter the molecule the more hydrophobic it is.

Platelets and RBCs are both non-nucleated cells.

Liver failure results in buildup of urea leading to increased blood ammonia levels and ultimately hepatic encephalopathy

Which porcesses will be active in a absorptive state?

Which jaundice? liver disease results in increased levels of uncon. and con. bilirubin and increases in urobliniogen.

Action potentials are reversible and vary in the degree of depolarization.

Where dose unconjugated bilirubin become conjugated bilirubin?

Select the follwoing factors of the clotting cascade that require Vitamin K as a cofactor.

In secondary hemostasis there are 3 separate pathways leading to formation of a clot: extrinsic, intrinsic and common

Which jaundice? Outflow of bile duct is impaired results in increases in conjugated bilirubin and colorless feces.

Which of the follwoing are functions of thromboxanes?

Liver glycogen is used as fuel reserve for muscle and muscle glycogen is used as a glucose reserve blood glucose levels.

At resting potential there is more sodium outside of the cell and more potassium inside of the cell.

______ is the preferred energy source for the brain, however, in times of starvation ____ can be used.

Mature hemoglobin has two identical dimers. When O2 is bound the structure is in its T-form.

Please list the six lipoproteins in order from lowest density to highest density.

Which of the following are functions of prostacyclin and/or prostaglandins?

Liprotein lipase is important in the __ of tracylglycerols and is activated by __ on the lipoprotein particles.

The intrinsic pathway occurs when factor _____ is acitvated by contact with phospholipids in the blood vessels.

The Nitrogen Sparing effect of Fat spares fat in times of starvation.

Which processes will be active in a post-absorptive state?

The main neurotransmitter released at the neuromuscular junction is Acetylcholine (Ach).

Leukotrienes function to decrease vascular permeability and aid in the inflammatory response by decreasing phagocytosis.

What are the three main components of plasma?

Platelets are activated by a complex to form a platelet plug. What components are involved in this complex?

Myelin is repsonsible for increasing current spread and speed.

Cholesterol is synthesized by all nucleated cells. What are the two main functions of cholesterol?

What is serum?

Which jaundice? Excessive RBC breakdown results in increased uncon. and con. bilirubin, hemoglobinuria and dark feces.