Arrive Ready Life Sciences Test

Question 1

How ready do you feel for the test?

Accepted Answer

Very ready!, Afraid, Half ready, Not ready at all

Question 2

Why are AT1s squamous in shape and cover over 95% of the alveolar barrier's surface area?

Accepted Answer

To increase the amount of gas exchange that can occur

Question 3

What are the distinct repair steps seen after an LPS-induced mouse lung injury mentioned in the review paper?

Accepted Answer

Cell proliferation, cell-cycle arrest, and trans-differentiation into AT1

Question 4

Classify this epithelium

Accepted Answer

Simple columnar

Question 5

What is the purpose of having teichoic acids embedded in Gram-positive cell walls?

Accepted Answer

To provide rigidity to the cell wall

Question 6

AT2s are referred to as facultative stem cells when

Accepted Answer

They exit quiescence and enter the repair program

Question 7

What is the difference between teichoic acids and lipoteichoic acids?

Accepted Answer

Lipoteichoic acids go down into the cytoplasmic membrane

Question 8

Using the HopX marker, AT1s are seen transforming into AT2s. Why isn't this seen using IGFBP2 for lineage tracing?

Accepted Answer

It is a marker for mature AT1s, which are mostly terminally differentiated

Question 9

What is a common characteristic of epithelial tissue

Accepted Answer

All of the above

Question 10

The alveoli epithelial barrier is exposed to many pathogens from the outside environment, how does it combat this?

Accepted Answer

By using self-renewal and differentiation

Question 11

The two dyes used in the Gram stain proceedure must be different colours

Accepted Answer

True

Question 12

Why have AT1s been studied less throughly than AT2s?

Accepted Answer

All of the above

Question 13

What part of the LPS layer is the line pointing to in this diagram?

Accepted Answer

Lipid A

Question 14

What is the correct order of layers from outermost to inner most for a Gram-negative bacteria?

Accepted Answer

Outer membrane, periplasm with peptidoglycan, cytoplasmic membrane

Question 15

The definition of tissues being a group of similar cells doing a similar function does not apply to

Accepted Answer

Connective tissue

Question 16

How did the paper we were assigned in week 3 identify that CV does not enter the cytosol?

Accepted Answer

Only one SHS transport event was observed and the TM graph plateaued once

Question 17

If you combine the Greek word for web or tissue and the word for branch of learning, you get

Accepted Answer

Histology

Question 18

Classify this epithelium

Accepted Answer

Simple cuboidal

Question 19

Why is mordant added after crystal violet in a gram stain proceedure?

Accepted Answer

To complex with the CV to make it harder to come out

Question 20

Gram-positive bacteria is mostly cocci and some bacilli

Accepted Answer

True

Question 21

How prepared do you feel for the test now?

Accepted Answer

Very ready!, Not ready at all, Half ready, Afraid

Question 22

Epithelial tissue always has connective tissue by it, but what is in between the two?

Accepted Answer

Basement membrane

Question 23

When classifying epithelium, which way are the number of layers counted from the basement membrane?

Accepted Answer

Perpendicular

Question 24

The core polysaccharide in the LPS layer can vary within a species, thus it is used to classify bacteria

Accepted Answer

False

Question 25

When using a Gram stain, which type of bacteria is purple?

Accepted Answer

Gram-positive

Question 26

Simple columnar tissue form microvilli, what are the functions of columnar tissue?

Accepted Answer

Transportation, absorption, secretion, and protection

Question 27

Transcellular transportation is a function of epithelial tissue, select which of the following that are also functions

Accepted Answer

Absorption, Sensation, Secretion, Protection

Question 28

Classify this epithelium

Accepted Answer

Stratified squamous

Question 29

Recent development of lineage tracing, 3D image construction, and scRNA-seq allowed more info on AT1s to be gained

Accepted Answer

True

Question 30

What is a repairation response during severe lung injuries?

Accepted Answer

Some airway epithelial cells move into alveolar parenchyma to help repair

Question 31

Epithelial tissues can be present as glands, which

Accepted Answer

Originate from invaginations of epithelial cells

Question 32

The classification of epithelium is written as

Accepted Answer

Number of layers + cell shape

Question 33

One of the main functions of AT2s is the production of surfactants. What happens when there is a dysregulation of this?

Accepted Answer

Defective lung repair after injury

Question 34

Functions of AT2 facultative stem cells are regulated by niche cells that sense injury. Which is a niche cell?

Accepted Answer

All of the above

Question 35

Simple cuboidal tissues form the ducts of many glands. What are the functions of simple cuboidal cells?

Accepted Answer

Secretion, absorption, and protection

Question 36

Even if neighboring cells look alike, they can have different responses to the same thing

Accepted Answer

True

Question 37

Which subtype of adult AT1s maintain plasticity and participate in repair/regeneration by transitioning into AT2s?

Accepted Answer

HopX+Igfbp2- AT1 cells

Question 38

What is the correct order of layers from outermost to inner most for a Gram-positive bacteria?

Accepted Answer

Peptidoglycan, cytoplasmic membrane, Peptidoglycan, periplasmic space, cytoplasmic membrane

Question 39

Which of the following is evidence that transient cell types from the repair process may cause some diseases?

Accepted Answer

All of the above

Question 40

Why is alcohol (or another decolourizer) added in a Gram stain?

Accepted Answer

To perforate the PM and release the CV from the Gram-negative bacteria

Arrive Ready Life Sciences Test

Questions 40

Arrive Ready Life Sciences Test

Questions 40