Clinical chemistry 1 extended

Which of the following steps in automation generally remains a manual process in most laboratories? 

If the concentration of an unknown exceeds the range of the standards how is the result displayed?

In monoclonal antibody production, the specificity of the antibody is determined by the 

Tandem mass spectrometers   

__ studies will show whether a method is able to accurately measure an analyte. A aliquot is added into a matrix and the

Analytic sensitivity refers to the ability of a test to

When a stat specimen can be analyzed out of sequence on an as-needed basis on a discrete analyzer, the instrument is sai

___or dynamic values from invivo monitoring of constituents in blood and other body fluids will revolutionize laborator

The strength of binding between an antigen and antibody is related to the 

_____ is based on cells transported under fluidic pressure passing one by one through a laser beam.

Possible sources of interference with sandwich immunoassays include

What analyzer uses Dry chemistry slides?

The power processor (beckman Coulter) performs what?

In ion-exchange chromatography, solute mixtures are separated by virtue of the magnitude and charge of ionic species.

A characteristic of percent transmittance is that it:

The stronger the affinity and avidity, the greater the possibility of cross reactivity.

For an enzyme to be used in an enzyme immunoassay, it must meet all the following criteria except:

Under standard conditions, the _____ of an AB is measured using a hapten because the hapten is a low molecular weight an

The affinity constant, K_a, of an antibody refers to the

Competitive immunoassays are radiolabeled antigen competing with unlabeled antigen for binding sites.

Which of the following correctly ranks electromagnetic radiation from low energy to high energy?

Which of the following is considered a define activity in the DMAIC methodology?

In order o deal with loss of blood gases for electrolyte testing , some manufacturers have introduced:

Which of the following chemistry analyzers uses slides to contain the entire reagent system? 

The government agency responsible for regulating laboratory instruments & reagents is

Which of the following approaches to analyzer automation can use mixing paddles to stir? 

The most common mass analyzer used today is:

Which of the following is NOT a way to preserve reagents?

In which of the following components of a chromatography instrument does selective separation of a mixture occur?

The parameters that are used to determine how good a given test is at detecting & predicting the presence of disease is

___ is an immune precipitation method that uses an electrical field to cause the AG and AB to migrate toward each other

Modifications in microsampling and reagent dispensing improve which of the following phases in clinical testing? 

All of the following are advantages to automation EXCEPT 

Which of the following is not an objective of proteomics research?

____ refers to the group of techniques used to separate complex mixtures on the basic of different physical interactions

Which is most accurate concerning ISEs?   

Reverse-phase liquid chromatography refers to:

Which of the following is false concerning the principles of point-of-care testing devices?

The most common form of batch analysis is

one reacted with antihuman IgA (α-chain– specific) reagent, and the other reacted with antihuman λ reagent. This is :

Mass spectrometry identifies analytes based on:

____ measures the light scattered

What is the purpose of analyze in the DMAIC methodology?

Dwell time refers to the 

Which unlabeled immune precipitation method in gel is used to quantitate a serum protein? 

DMAIC stands for (DEFINE,MEASURE,ANALYZE,IMPROVE,CONTROL)

The stronger the affinity and avidity, the possibility of ___

Which of the following is NOT a component of a HPLC?

The major role of polyclonal antibodies in the clinic is :

___ is the difference between true value and measured value

If the concentration of an unknown exceeds the range of the standards the result is printed with

The use of a _____to immobilize reagent Ab or Ag provides a method to separate free from bound labeled reactant after

A characteristic of absorbance is that it:

The major disadvantage of continuous flow automated testing system is

Of the following which is not a component of a spectrophotometer?

The actual measurement of each aliquot for each test must be accurate. This is accomplished through _______of a sample

All of the following are primary considerations in the selection of an automated chemistry analyzer EXCEPT 

an important evaluation if the total allowable analytical error is less than the random and systemic errors (total erro

In flow cytometry, the side scatter is related to the 

If the amount of Ag exceeds the amount of Abs supplied y test kit, cross linking is decreased, and the assay is in ____

___ measures the light transmitted

Which is the most sensitive detector for spectrophotometry?

Layers of slides used in VITROS analyzers may contain:

PCR/ESI-TOF has the distinct advantage in pathogen identification because:

Which of the following is NOT a driving force for more automation? 

What is the purpose of the chopper in an atomic absorption spectrophotometer?

ISE are designed to be sensitive toward individual ions

The most sophisticated approach that is commonly used today to properly identify & locate a sample in analyzer is

Reflectance spectrometry uses which of the following? 

The simplest way to identify an assay is by the ____

A second and unique type of dry reagent for the VITROS analyzer includes a multilayered:

This substance causes major interference in many analyses.

____ measures concentration of particulate matter in a sample

What components are used in gas spectrophotometry?

Two reactions must be coupeld and one reaction compared w other to measure electrochemical activity of ____

___ is a graphical representation of observed values of control material over time in the context of the upper & lower l

In general terms, the variance is the ___ of the ___

The coefficient of variance, expressed as a decimal value, is calculated using

Which of the following procedures is not currently or routinely used for point-of-care testing devices?

In nephelometry, the antigen–antibody complex formation is enhanced in the presence of 

The colored belt designations are given to different levels and types of training in which of the following

Drugs of abuse are typically measured by:

In comparison of method studies, the primary goal is to

Reagent Systems can be delivered either ___ or ____

An example of a modular integrated chemistry/immunoassay analyzer would be the 

Which of the following is not an advantage of CE?

In high-performance thin-layer chromatography (HPTLC), developed bands are compared with reference standard concentratio

Luminescent labeling reactions depend on the use of:

____ is the separation of each sample in a separate container while ____ uses force generated by centrifugation

The difference between heterogeneous assays and homogenous assays are that in homogenous assays:

Photometry:

Modular analyzers are unique for their

Which of the following best describes the process of fluorescence?

Chemical reaction phase includes

Migration of charged solutes/particles in an electrical field is known as ____

Which of the following regarding MS is false?

Which of the following statements is TRUE?

Immunoprecipitation reactions are routinely performed in the clinical laboratory

Which of the following would be considerred pre-analytical?

Binding is related to all of the following except: