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Micro exam part 2
Micro exam part 2
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Questions
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Answers
1
Secretory phospholipase A2 has activity against which type of pathogen:
Gram +
Gram -
Molds
Virus
2
You should be admitted to the hopsital for fungal keratitis.
True
False
3
The following pt is a contact wearer, what would be your top differntial diagnosis?
viral kertatitis
bacterial keratitis
acanthomoeba keratitis
Fungal keratitis
4
What factors may be promoting this condition?
Tear proteins
Type I Hypersensitivity
Type IV Hypersensitivity
Mechanical interaction
5
There are more than 500 proteins found in the tear film.
True
False
6
Ocular toxoplasmosis can result in a chorioretinal scar.
True
False
7
Complement results in a chronic inflammatory response.
True
False
8
What is likely to be seen 1-2 weeks after an EKC infection?
corneal scarring
subepithelial infiltrates
psuedomembrane
dendrites
9
Complement system stimulates phagocytes to clear foreign and damaged materials & activates other cells for phagocytosis.
True
False
10
Hutchinson's sign is due to an infection of what?
miebomian glands
Corneal epithelial
V1 of the trigeminal
Bulbar conjunctiva
11
What tests would you want to perform to find a diagnosis for the following presenation
seidel test
Confocal microscopy
culture
PCR
12
Pharyngoconjunctival fever is caused by which THREE adenovirus serotypes?
5
7
3
11
13
The worst symptom of Presumed Ocular Histoplasmosis is:
Histo spots
Dry eye
Choroidal neovascularization/macular scar
Peripapillary atrophy
14
How would you treat ocular toxoplasmosis?
IV antibiotics
Oral antibiotics
triple therapy
Topical antifungal
15
Which crainial nerve is being affected?
Vegas
Trigeminal
My
Facial
16
Which mucin(s) are gel forming?
MUC5Ac
MUC16
MUC1
MUC4
17
Herpes Zoster Ophthalmicus presents with which of the following symptoms?
conjuntivitis
dendrites
meibomian dysfunciton
Pseudodentrites
18
Fungal keratitis is described by
Lesions in central vision
subepithelial infilrates (spores)
feathery infiltrate
lesions in the peripheral cornea
19
Pharyngoconjunctival fever is caused by which virus?
Herpes Simplex Virus
Varicella Zoster
Adenovirus
Adeno-Associated virus
20
All of the following are symtpoms of Pharyngoconjucntival fever EXCEPT
+ PAN
Conjunctival follicles
watery discharge
Hypopyon
21
Which structures produce the antibody IgA?
conjunctival lymphoid tissue
accessory lacrimal gland
meibomian gland
lacrimal gland
22
EKC is a highly contagious infection.
True
False
23
Symptoms of a demodex infestation include what? select all that apply
foreign body sensation
mild/moderate itching
Extreme redness
burning
24
Cytomegalovirus is more severe in patients with what underlying health issues?
Cardiac disease
diabetes
Dry eye
AIDS
25
What are the top 2 reasons why patients overwear their contact lenses?
Forgetting
Saving money
Comfort
doctor recommendation
26
What is the mos likely instigator of the condition given the timing?
cats
Flowering grasses
molds
ragweed
27
The Aqueous layer includes:
MUC5AC
salts
non-polar lipids
proteins
28
EKC treatment regimine includes which of the following? (select all that apply)
topical antibiotics
palliative treatement
Betadine
warm compress
29
Which of the following are NOT consistent with the research related to children wearing contact lenses?
contact lenses help children with social acceptance
doctors can typically tell the first visit if the child is a good condidate
contact lenses can help children with sports performance
children are at greater rick of eye infections than young adults
30
Molds grow as single sells & use budding for reproduction.
False
True
31
What is the normal blinking rate?
10-16 times/min
7-12 times/min
16-20 times/min
5-10 times/min
32
The initial ocular surface response to a pathogen is through
immune privilege
antibicotics
innate
adaptive
33
IgA neutralizes pathogens by preventing their attachment to a host cell.
True
False
34
Which mucin(s) are membrane bound?
MUC16
MUC5Ac
MUC4
MUC1
35
Components of the Lipid Layer include:
non-polar lipid layer
Mucins
itnercalcated proteins
polar lipid layer
36
How is cytomegalovirus detected?
Signs/Symptoms
PCR
Culture
ELISA
37
What treatment would you adminster for this patient?
stop CL wear
topical antibiotics
systemic virals
systemic antibiotics
38
What is shown below?
Bacterial conjunctivitis
Pediculosis
Demodex
Fungal keratitis
39
What pathology is shown below?
Fulminant Retinitis
Indolent Retinitis
Retinitis pigmentosa
Retinal bleaching
40
What is shown in the photo?
superficial infiltrates
Corneal scarring
subepithelial infilrates
Dry eye
41
The main funtions of mucins include:
Prevention of adherence of P. arginosa.
Lubrication
janitoral
evaporation
42
What percent of the tear film protein does lactoferrin account for?
20-30%
5-10%
15-20%
10-15%
43
Confocal microscopy is used to diagnose acanthamoeba keratitis.
True
False
44
Where is the corneas only lympathic tissue located?
Near the punta
Near the plica semilunar
Near the limbus
In the eyelid margin
45
What is the estimated risk of developing a microbial keratitis if you are NOT a contact lens wearer?
10-12/10,000 patient years
2-4/10,000 patient years
20-25/10,000 patient years
1/10,000 patient years
46
Viral conjunctivitis/epidemic keratoconjunctivitis (EKC) is caused by which serotypes of adenovirus?
37
19
8
7
47
What protein has the highest concentration in tears?
lipocalin
lactoferrin
lysozyme
complement
48
What percentage of the tear protein is lysozyme
5-10%
10-15%
30-40%
20-30%
49
How would you treat this patient? Select all that apply.
Oral antivirals
oral antibiotics
Topical antivirals
Steroids
50
32 y/o CL wearer reports itchy eyes. symptoms started this & last year in March. What is your diagnosis?
Giant papillary conjunctivitis
Allergic conjunctivitis
vernal keratoconjunctivitis
Atopic keratoconjunctivitis
51
All of the following are responsible for fungal keratitis, which one is a yeast?
Candida
Fusarium
claudosporium
Asperiagillus
52
These pictures are taken two days apart. What do you suspect the infection is now?
Corneal edema
Herpes Simplex Keratitis
Fungal keratitis
bacterial keratitis
53
What is the most common cause of posterior uveitis?
herpes simplex keratitis
acanthamoeba castellanii
Histoplasma capsulatum
Toxoplasma gondii
54
Shingles are primarily on the head/face.
True
False
55
Ocular immune privilege is due to: (select all that apply)
Blood-retinal barrier
salt concentration
Inhibition of lymphocytes
Regulation
56
Cytomegalovirus remains latenty where in the body?
Facial nerve
V1
V3
myeloid in bone marrow
57
What treatment regimen should you use?
discontinue CL wear
Topical antibiotic
combination antihistalmine/ Mast cell stabilizer
Topical steroid
58
Blood typing is needed for a corneal transplant.
False
True
59
How would you treat a patient with cytomegalovirus?
IV antivirals
topical antivirals
Steroids
systemic antivirals
60
The literature suggests that contact lenses increase your risk of developing COVID-19.
False
True
61
Lipocalin can bind which two things?
siderophores
debris
salts
lipids
62
Most often, complement ends with cell lysis.
False
True
63
What is the top reason established contact lens wears, stop wearing contact lenses?
discomfort
vision
cost
handling
64
Chickenpox is caused by which virus?
Poxvirus
cytomegalovirus
HSK
Varicella Zoster Virus
65
Internal ocular structures are primarily served through what?
immune privilege
antibicotics
innate
adaptive
66
What causes acanthamoeba keratitis?
mold
bacteria
yeast
ameoba
67
The pt presents with pain and a history chicken pox
Shingles
ACC
EKC
Herpes Simplex
68
Fungal keratitis can be treated with either topical or systemic antifungals.
True
False
69
All of the following are signs/symptos of acanthamoeba keratitis EXCEPT:
epithelial psuedodondrites without ulceration
subepithelial infilrates
serous drainage
photophobia
70
EKC usually starts unilaterally and becomes bilateral.
True
False
71
Your patient returns 2 days later with the following progression, what is your disagnosis?
yeast infection
fungal keratitis
bacterial keratitis
acanthameoba
72
What is shown below?
Bacterial conjunctivitis
Pediculosis
Demodex
Fungal keratitis
73
What would be the best treatment plan?
oral steroid
discontinue contact lenses
combination antihistamine/ mast cell stabilizer
Topical antibiotic
74
What pathology is shown below?
Retinitis pigmentosa
Fulminant Retinitis
Indolent Retinitis
Retinal bleaching
75
Treatments options for Pharyngoconjunctival fever include what? (select all that apply)
Topical steroids
Topical antiviral
pallative treatment
betadine regimine
76
Treatments for demodex include all of the foollwing EXCEPT:
intense light pulsation
opthalmic ointments
pallative care
Tea trea oil
77
The Glycocalyx layer includes:
mucins 1,4 & 16
glycoproteins
polar lipids
salts
78
Signs of Cytomegalovirus include: (select all of the following)
CD4 T cell count below 50
Corneal edema
Extreme Dry eye
Seidel test staining
79
EKC can progress to have a pseudomembrane and a conjunctival hemorrhage.
False
True
80
26 y/o male CL wearer. Mild irriation OS/OD. Reports CL's have been dirty & moving a lot. What is your diagnosis?
Vernal Keratoconjunctivitis
Giant Papillary Conjunctivitis
Atopic Keratoconjunctivitis
Allergic conjunctivitis
81
Intial CMV infection symptoms include what? Select all that apply.
fever
red eye
sore throat
watery eyes
82
Presumed ocular hisoplasmosis has never been seen as an active infection.
True
False
83
Lipocalin accounts for 25% of basal tears.
True
False
84
What makes treating acanthamoeba keratitis difficult?
The infector uses a cyst to remain dormant
There is no treatment
The treatent is not efficacious
85
A patient has the follicular ocnjunctivitis, eyelid edema with watery discharge. What would be your diagnosis
Dry eye
Shingles
EKC
PCF
86
What type of infectin is shown below?
fungal keratitis
viral keratitis
bacterial keratitis
acanthamoeba keratitis
87
What would be your top diagnosis for the following pathology?
external hordeolum
demodex
pediculosis
bacterial conjuctivitis
88
What is the estimated risk of developing a microbial keratitis if you ARE a contact lens wearer?
1/10,000 patient years
20-25/10,000 patient years
10-12/10,000 patient years
2-4/10,000 patient years
89
Shingles should be treated with which of the following regimines? (select all that apply)
topical antibiotics
Systemic steroids
topical steroids
Oral antivirals
90
Acanthamoeba keratitis causes extreme pain.
True
False