Viro block 6- Tx, prevention + control of viral Dz + Poxviridae

Question 1

Your samples got mixed up. You perform histopath on all samples & find ATI inclusion bodies.What virus can be ruled out?

Accepted Answer

avipox

Question 2

Avipoxviruses have characteristic inclusion bodies. Which inclusion body are intracytoplasmic eosinophilic and granular?

Accepted Answer

Bollinger bodies

Question 3

Poxviruses show an extraordinarily high resistance to drying. And can survive for many years in dried scabs

Accepted Answer

True

Question 4

Replication of poxviruses occurs predominantly, if not exclusively in the ______

Accepted Answer

cytoplasm

Question 5

The benign form of sheeppox includes the deposition of lesions on the skin, pharynx,larynx,lungs,vagina,abomasum& spleen

Accepted Answer

False

Question 6

What is false regarding DIVA vaccines?

Accepted Answer

Passive transfer via colostrum renders the DIVA method useless., Prior viral exposure won’t hinder the efficacy measurement of the vaccine

Question 7

Which is not a viable method of Poxvirus diagnosis

Accepted Answer

all are methods

Question 8

Agglutination is a method using the properties of specific antibodies to bind many antigens into single clumps

Accepted Answer

True

Question 9

Severe cases of Orf may include lesions on genitals, coronets, and ears. Scrotal lesions can cause infertility

Accepted Answer

True

Question 10

Which of the following poxviruses can be transmitted via biting arthropods?

Accepted Answer

both

Question 11

Which of the following is true regarding vaccination against contagious ecthyma

Accepted Answer

In problem herds/ lams and kids should be vaccinated at 6-8 weeks, is an example of a scarification vaccine, vaccine is prepared from suspension of scabs in glycerol saline.

Question 12

Which of the following is a differential diagnosis of pseudocowpox

Accepted Answer

bovine herpes virus ulceratice mammilitis, vesicular stomatitis, cowpox, black spot

Question 13

infections of pseudocowpox are generally mild and lesions are characterized by hyperplasia of squamous epithelium

Accepted Answer

True

Question 14

primary viremia disseminates the virus back to the skin and to other target organs

Accepted Answer

False

Question 15

utilization of a ____ vaccine is the best way to differentiate infected animals from vaccinated animals

Accepted Answer

subunit

Question 16

what is false regarding the prevention and control of viral disease

Accepted Answer

Quarantine=effective wth DZ involving chronically infected healthy carriers, Isolation applies to those who have been exposed to a contagious disease

Question 17

You perform a complement fixation test for Dr. Toka, you notice that the sheep RBCs were lysed at the end of the test

Accepted Answer

You let Dr. Toka know the initial sample did not have unknown antibodies, you let him know that the test yielded a negative reaction

Question 18

A direct FAT test utilizes a secondary fluorescent-labeled antibody to detect the primary antibody from a patients serum

Accepted Answer

False

Question 19

Poxviruses can either be enveloped(EEV) or non-enveloped(IMV). EEV is non-infectious.

Accepted Answer

False

Question 20

Good luck friends! You guys are gonna crush this!

Accepted Answer

Virology is my middle name, I got this in the bag, 10/10 for me this week 🥳, Heck yeah, I am! Thx library gremlin

Question 21

Acute lesions of pseudocowpox result in thick scabs that become elevated due to the accumulation of

Accepted Answer

granulation tissue

Question 22

Cowpox can be diagnosed upon id of the pathognomonic horseshoe-shaped ring of small scabs after a thick scab falls off

Accepted Answer

False

Question 23

A live attenuated virus vaccine retains its antigenicity but loses its virulence.

Accepted Answer

True

Question 24

Which of the following viruses are part of the parapoxvirus genus

Accepted Answer

pseudocowpox, bovine papular stomatitis virus, contagious ecthyma

Question 25

Contagious Ecthyma (orf) is a worldwide parapox virus primarily significant in

Accepted Answer

kids (young goats.... not.... you know), lambs

Question 26

You are helping Dr. Ketzis study hematopinus suis.You remember that it mechanically transmits swinepox to pigs. Swinepox

Accepted Answer

Piglets can be born with/develop lesions in the upper resp +digestive tract, has recorded evidence of transplacental transmission of neonatal pigs, is a member of the genus suipoxvirus, can be seen with greasy pig disease and secondary bacterial dermatitis, Has a high case fatality in congenitally infected and suckling pigs

Question 27

While helping Dr. Ghosh with poop research, he asks you to eliminate all forms of microorganisms on the poop sample cup.

Accepted Answer

you sterilize the poop cup

Question 28

following introduction into the body, poxvirus usually gains access to systemic circulation via

Accepted Answer

lymphatic system

Question 29

Select the correct properties of Poxviruses

Accepted Answer

Parapoxviruses=covered in long thread-like tubules- criss-cross arrangement, typically brick-shaped, pleomorphic, irregular surface, BOTH Orthopoxviruses and Parapox viruses have complex symmetry

Question 30

You are j-chillin in the union. Dr. Ghosh airdrops you a quiz.Select the correct matches for 2 extra pts on your block

Accepted Answer

Tamiflu- Influenza A + B, Acyclovir - Herpes, AZT + ZDV - retroviruses

Question 31

Select the true statements regarding poxviruses genome

Accepted Answer

encode proteins that fxn in nucleic acid synthesis, encode proteins that counteract host adaptive+innate immune responses, genome of poxviruses = single molecule of linear double-stranded DNA

Question 32

Dr.Ghosh really likes throwing pop quizzes your way.He asks you to talk to him about Contagious Ecthyma.What do you say?

Accepted Answer

first lesions develop in the mucocutaneous jxn., necrosis + sloughing of the affected epodermis + stratum papillare=observed, Previous damage to the skin is essential in order to establish infection, anorexia and weigtloss due to oral lesions, cutaneous response = type IV hypersensitivity and influx of inflam cells

Question 33

Monkeypox is another species from the orthopox genus. Which of the following is true?

Accepted Answer

symptoms similar to small pox, handling infected monkeys, Gambian rats+squirrels result in human infection, viral zoonosis

Question 34

Sheeppox is a reportable disease, goat pox is a notifiable disease

Accepted Answer

False

Question 35

uncomplicated cowpox infxn in cats end with scabs healing in ~6 wks. 2ndary BacT infnxs may cause coryza+conjunctivitis

Accepted Answer

True

Question 36

Which vaccine strategy against sheeppox offers protection >1 year

Accepted Answer

live attenuated

Question 37

Utilization of ethylene oxide and ozone are _____ methods of sterilization

Accepted Answer

chemical

Question 38

The following are methods of pseudocowpox treatment:

Accepted Answer

Removal of scabs, Application of emollient ointment before milking

Question 39

You run into Dr. Ghosh at beach fest. He asks you to tell him the benefits of Immunochromatography: point-of-care tests

Accepted Answer

easy to carry, simple to perform, does not require specialized equiptment

Question 40

Sheep Pox, Goat pox & lumpy skin disease are from the genus Capripoxvirus. they are highly contagious viruses endemic in

Accepted Answer

Asia, Parts of europe, Africa

Question 41

Cowpox has worldwide distribution

Accepted Answer

False

Question 42

acute lesions of pseudocowpox, once the thick scab falls off, you&#x27;re left with a signet-shaped ring of small scabs

Accepted Answer

False

Question 43

What makes an enveloped poxvirus different from other enveloped viruses

Accepted Answer

lower lipid content=less sensitive to organic solvents/disinfectants, high environmental stability- infectious for months in ambient environments

Question 44

In Basseterre,u find this needy cat.W/o thinking, you pick him up+hug him. Are you at risk for cowpox if he is infected?

Accepted Answer

yes.Cowpox =not common in cows. cats = more likely to transmit to humans

Question 45

Intracellular viral particles only have an inner membrane. IMV comes out by disruption of host cell.

Accepted Answer

True

Question 46

Live attenuated vaccines are produced from

Accepted Answer

Naturally occurring attenuated viruses, attenuation of viruses by selection of cold-adapted mutants + reassortments, attenuation of viruses by serial passage in heterologous hosts, attenuation of viruses by serial passage in cultured cells

Question 47

Amantadine has been shown to reduce clinical signs in FIV + cats when administered at a dose of 10mg/kg bid,SQ, Q3 weeks

Accepted Answer

False

Question 48

Most poxviruses are not enveloped and are released via cell lysis

Accepted Answer

True

Question 49

which of the following is not in the genus: orthopox

Accepted Answer

lumpy skin disease, pseudocowpox, Orf virus, sheep pox

Question 50

What assays rely on the property of pathogens to nonspecifically agglutinate erythrocytes?

Accepted Answer

Hemagglutination inhibition, Hemagglutination

Question 51

Dr.Ghosh hands you PPE + asks you to take samples from animals with poxviruses in st kitts.What material do you collect?

Accepted Answer

vesicular fluid, crusts and scabs, skin lesion scrapings

Question 52

Disinfection is less effective than sterilization. it does not kill bacterial spores

Accepted Answer

True

Question 53

Acyclovir is a synthetic nucleoside of:

Accepted Answer

deoxyguanosine, DGTP

Question 54

A decrease in signal (positive result) when using a competitive eliza would ______ in the sample:

Accepted Answer

confirm the presence of an unknown antigen

Question 55

Poxvirus has a dumbbell-shaped core that acts as a storage vessel and 2 lateral bodies containing the viral genome

Accepted Answer

False

Question 56

Fowl pox is a member of the genus Avipox. Wich of these statements are false?

Accepted Answer

cutaneous form= wet form of the dz. Diptheric form= dry form of fowlpox, The wet form =characterized by small papules on the comb, wattles, and beak

Question 57

(1)_______ are slightly basophilic+composes of viral particles+ protein aggregats. (2)______ are strongly eosinophilic

Accepted Answer

(2) Type A- ATI inclusion bodies, (1) Type B- Guarnieri inclusion bodies (contained by most pox viruses)

Question 58

Because of the possibility of false +, quarantine is sufficient if an animal tests + but does not show clinical signs.

Accepted Answer

False

Question 59

Administration of protease inhibitors make it so HIV polyproteins can not be cleaves into functional proteins

Accepted Answer

True

Question 60

Pseudocowpox can be transmitted :

Accepted Answer

calves get infected from suckling on infected teats, contaminated milkers hands + teat cups, biting insects, spermatic fluid of bulls

Question 61

There has been a global rise in ulcerative dermatosis of sheep. What do remember about this disease from taking Viro?

Accepted Answer

associated lesions are usually raw craters that bleed easily, can be transmitted via damaged skin and coitus, 2 forms. Leg+lip ulceration and venereal form, Causes rams to be unfit for natural breeding

Question 62

Poxviruses are highly endotheliotropic, causing cutaneous skin lesions

Accepted Answer

False

Question 63

Radiation is a sterilization method. Which of the following is a method of non ionizing radiation?

Accepted Answer

ultraviolet rays

Question 64

You attend poxvirus trivia night at shiggity shack. Which of the following facts regarding cowpox in cows is correct?

Accepted Answer

cow-cow transmission involves teat cups or infected milkers hands, Suckling cows can develop lesions in the mouth, vesicles on the teat of a cow rupture, leaving ulcerated areas > form scabs

Viro block 6- Tx, prevention + control of viral Dz + Poxviridae

Questions 82

Viro block 6- Tx, prevention + control of viral Dz + Poxviridae

Questions 82