Regulatory Strategies of Enzymes

Question 1

Contractions during labor is an example of ...

Accepted Answer

positive feedback

Question 2

Allosteric modulators bind to the .... subunit of the enzyme

Accepted Answer

regulatory

Question 3

The enzyme that catalyses the biosynthesis of pyrimidines is ....

Accepted Answer

aspartate transcarbamylase

Question 4

... is an allosteric activator

Accepted Answer

ADP

Question 5

... is an allosteric inhibitor

Accepted Answer

ATP

Question 6

Which of the following is not a strategy for enzyme regulation

Accepted Answer

Ionic stabilization

Question 7

The form ".." of glycogen phosphorylase is the active form for glycogen degradation

Accepted Answer

a

Question 8

... catalyze phosphorylation

Accepted Answer

protein kinases

Question 9

... and ... are the most common covalent modifications of enzymes

Accepted Answer

acetylation and phosphorylation

Question 10

In the absence of substrate, ATCase is in ... state

Accepted Answer

T

Question 11

Allosteric regulation is mostly facilitated by covalent binding

Accepted Answer

False

Question 12

In the presence of ....., Vmax is decreased

Accepted Answer

Non-competitive inhibitor

Question 13

LDH is released during tissue damage, thus it is a ... of common injuries and disease

Accepted Answer

biomarker

Question 14

Which of the following is NOT a part of gene/mRNA regulation?

Accepted Answer

Phosphorylation

Question 15

Which of the following is NOT why phosphorylation is an effective way to regulate proteins?

Accepted Answer

Phosphate group can form nitrogen bonds

Question 16

Enzymes that have differences in amino acid sequence but catalyze the same reaction are called

Accepted Answer

Isoenymes

Question 17

Most covalent modifications of enzymes are reversible

Accepted Answer

True

Question 18

The activation of a zymogen mostly initiates a(n) ... of enzymatic reactions

Accepted Answer

cascade

Question 19

Digestive enzymes, blood clotting factors, insulin and apoptosis cascade are examples of ....

Accepted Answer

zymogens

Question 20

Zymogens are ...

Accepted Answer

inactive precursors of enzymes

Question 21

The key zymogen that initiates the blood clotting is ..

Accepted Answer

Prothrombin

Question 22

Proteolytic enzymes have specific inhibitors to prevent premature activation of the enzyme

Accepted Answer

True

Question 23

.... is a key enzyme in zymogen activation of digestive enzymes in pancreas

Accepted Answer

Trypsin

Question 24

In ATCase binding of the CTP keeps the enzyme at T state, as a positive modulator

Accepted Answer

False

Question 25

Most of the metabolism reactions in our body are regulated through .....

Accepted Answer

supply and demand balance, negative feedback

Question 26

Allosteric regulation can only be inhibitory

Accepted Answer

False

Question 27

Both hemoglobin and ATCase represent ....

Accepted Answer

positive cooperativity

Question 28

When the structure of modulator is quite different from substrate, it's called ... modulation

Accepted Answer

heterotropic

Question 29

If there is a tissue damage within the heart, the ... isoenzyme of LDH is expressed higher

Accepted Answer

H4

Question 30

Zymogens are activated via ...

Accepted Answer

proteolytic cleavage

Regulatory Strategies of Enzymes

Questions 30

Regulatory Strategies of Enzymes

Questions 30