BOC Blood Bank-Physiology & Serology

what is the most likely cause of the ABO discrepancy

which DAT results are associated w/ anamnestic antibody response in recently transfused patient

blood specimen from a pregnant woman is found to be B- w/ anti-D (titer:512). what is the best for exchange transfusion

patient types as O+ & crossmatched w/ 6 units. at IAT, both screens & 2 units are incompatible. what is the cause

a blood component used in treatment of hemophilia A is

in the process of IDing an antibody, the tech observes 2+ w/ 3/10 cells at IS. no reactivity after incubation or AHG.

transfusion of which of the following is needed to correct hypofibrinogenemia due to DIC

which is most probably explanation for these results

anti-E is IDed in a panel at AHG phase. when check cells are added no agglutination is seen. best course of action is

the purpose of testing w/ anti-A,B is to detect

use of EDTA plasma prevents activation of classical complement pathway by:

the ABO discrepancy seen is most likely due to...

which of the following might cause false-negative IAT

crossmatch results at AHG are negative. 1 drop check cells added, no agglutination seen. the most likely explanation is:

results are consistent with

results of a serum sample tested give presumptive antibody to high incidence antigen. further investigation should be...

rosette test will detect fetomaternal hemorrhage as small as

cephalosporin can cause positive DAT w/ hemolysis by which mechanism

RhIG administration would not be indicated in Rh- woman who has an

in the DAT, the antiglobulin reagent is used to

major crossmatch will detect

which test is most commonly used to detect antibodies attached to patient rbc in vivo

in cold autoadsorption procedure, pretreatment of patient cell w/ which reagent is helpful

25yo Caucasian woman (G3,P2) needs 2 RBCs. what is the cause of the positive panel

a reason why a patient's crossmatch may be incompatible while the antibody screen is negative is

what is the best interpretation

which antigen gives enhanced reactions w/ enzyme treated cells

results of Kleihauer-Betke stain indicate fetomaternal hemorrhage of 35 mL of whole blood. how many vials of RhIG

while performing routine postpartum testing for an RhIG candidate, a weak + antibody screen was found fro anti-D. why

in acid elution, 30/2000 cells had fetal hgb. policy is add 1 vial when volume is >20mL. how many vials RhIG needed

mixed field agglutination encountered in ABO grouping w/ no history of transfusion would most likely be due to

of the following, the most useful technique to ID & classify a high-titer low-avidity (HTLA) antibody is

10yo F hospitalized b/c red urine. PT recently recovered from upper respiratory infection, was pale & lethargic. PT has:

25yo Caucasian woman (G3,P2) needs 2 RBCs. what antibody cannot be ruled out

to prevent graft-vs-host disease, rbcs for infants who receive intrauterine transfusions should be

what is true of all 3 antibodies: anti-Fya, anti-Kka, & anti-K

which antibody cannot be excluded

the following was obtained from pre-transfusion reaction. what is the most probable cause

a pregnant woman has a positive screen. what is the association of antibody(ies) w/ HDFN

some blood group antigens characteristically hemolyze appropriate red cells in the presence of

what is the most likely explanation

an antibody that causes in vitro hemolysis & reacts w/ red cells of 3/10 crossmatched donors is most likely

which is an indicator of polyagglutination

patient serum is 1+ w/ 16/16 group O panel cells at AHG. auto was negative. test w/ ficin treated cells show 0. which Ab

which of the following is characteristic of Tn polyagglutinable red cells

the following test are noted for a unit of A- labeled blood. what should be done next

during emergency situations when there is no time to determine ABO group & Rh type patient is known A-. tech should...

what info is essential on patient blood sample labels drawn for compatibility testing

criteria determining RhIG eligibility include

what is the most appropriate diluent for preparing an 8% bovine albumin solution for red cell control reagent

26yo F w/unknown anemia. request for 6 RBC units. PT is A- w/ no history of transfusion/pregnancy. best way to find unit

patient is A2B+ & has anti-A1 in serum. he is in OR bleed and A2B cells are not available . what is the best choice

the Liley method of predicting severity of HDFN is based on amniotic fluid

a mother is Rh- and father is Rh +. baby is Rh-. what can be concluded

AHG (Coombs) control cells:

what is the most appropriate interpretation for lab data when Rh - mom has Rh + baby

which antigen is most likely to be involved in HDFN

group B- patient has positive DAT. which would occur

HLA antigen typing is important in screening for

which of the following would most likely be responsible for an incompatible antiglobulin crossmatch

56yo F w/ cold agg has positive DAT. when DAT is repeated w/ monospecific antiglobulin, which is most likely detected

29yo M is hemorrhaging severely. he is AB-. 6 units required STAT. what is the preferrable, available type

based on the panel, the most likely antibodies are

PT serum contains a mixt of antibodies. One is anti-D. anti-Jka, anti-Fya & another are present. what technique will ID

is exchange transfusion is necessary, the best choice of blood is:

in suspected HDFN cases, what significant info can be obtained from baby's smear

a 10% cell suspension is used for compatibility testing. which would most likely occur

10 mL fetomaternal hemorrhage in Rh- woman delivering Rh+ baby means

which medication is most likely to cause production of autoantibodies

which of the following is useful for removing IgG from red cells w/ positive DAT to perform a phenotype

what is the cause of incompatibility of donor 1

what is the most likely cause of the discrepancy

does baby have HDFN

unit of FFP was thawed & immediately refrigerated at 4C on Monday. the next evening it was transfused as replacement f

which of the following explains an ABO discrepancy caused by problems w/ patient red cells

a man suffering from GI bleed received 20 units of RBCs in 24 hrs & still oozing. what product should be administered?

specimen types as A+ w/ negative screen. 6 units of A+ were crossmatched & 1 was incompatible at AHG. what is next

which of the following would be best source of PLTs for transfusion in case of alloimmune neonatal thrombocytopenia

an antibody screen performed w/ solid phase technology revealed a diffuse layer of rbc on bottom on well. this indicates

Kleihauer-Betke stain revealed 0.3% fetal cells. what is the estimated volume (mL) of fetomaternal hemorrhage

25 y/o Caucasian woman (G3 P2) required 2 RBC units. her screen was positive, panel below. what cannot be ruled out

mom is A w/ anti-D in serum. what would be preferred blood product for intrauterine transfusion

which of the following antibody screen results would you expect w/ the ABO discrepancy

which of the following patient data reflects the discrepancy of a person's red cells demonstrate acquired B

in the DAT & IAT, false negative reactions may result if the

mechanism that best explains hemolytic anemia due to penicillin is...

which lectin should be used first to resolve this discrepancy

transfusion of Ch+ red cells to patient w/ anti-Ch causes

a newborn demonstrates petechiae, ecchymosis & mucosal bleeding. the preferred blood component for this infant would be

an OB patient had 3 pregnancies. 1 was healthy, 2 was jaundiced & required exchange transfusion, 3 was stillborn. why?

PT serum is 2+ in AHG w/ all cells & own cells. received transfusion 6 mo ago. optimal adsorption method to remove Ab is

anti-I may cause positive DAT b/c of

which represent acceptably IDed patient for sample collection & transfusion

granulocytes for transfusion should

to confirm antibody specificity as anti-P1, a neutralization was performed. what conclusion can be made from the result

samples from same patient were received 2 days in a row. how should crossmatch be performed

a persons saliva incubated w/ antibodies & tested w/ A2, O, & B indicator cells. the persons ABO phenotype is:

a patient received 4 units 2 years ago & has multiple antibodies. it is most helpful to

which is the preferred specimen for initial compatibility testing in exchange transfusion therapy

patient in immediate bone marrow transplant period has hct 21%. the red cell product of choice is

which antibody is most likely present

a serological centrifuge is recalibrated for ABO testing. the centrifuge time should be

process of separation of antibody from its antigen is known as

weakly reactive anti-D is detected postpartum of Rh- woman. all screens were negative prenatally. findings indicate...

the test for weak D is performed by incubating patients red cells w/

polyspecific reagents used in DAT should have specificity for

performing antibody screen, a test reaction suspected rouleaux. saline replacement performed & reaction remains. why

based on the panel, which technique would be most helpful in determining antibody specificity

what clinical condition is consistent w/ the lab results shown below

to confirm specificity for anti-Leb, an inhibition study was performed w/ Lewis substance. what conclusions can be made

on Monday, patient's was antigen K+. 2 days later, the patient typed K-. Patient given 2 FFP units. Tech concluded that:

the goal of exchange transfusion is to remove infant's Ab-sensitized rbc & control hyperbilirubinemia & choice unit is

patient received 2 units & had DHTR. pre-transfusion screen was negative. repeat testing detected antibody at AHG. why

what is the next step

what happens to an antibody in neutralization study when a soluble antigen is added

40yo man w/ autoimmune hemolytic anemia due to anti-E has hgb 10.8 g/dL. patient will be treated with:

DR antigens in HLA system are

which component is most appropriate to transfuse an 8yo male hemophiliac about to undergo minor surgery

what should be done next

an ABO discrepancy was thought to be due to antibody against typing sera. which test would resolve this

which of the following is a characteristic of polyagglutinable red cells

blood selected for exchange transfusion must

serum from group O, Cde/Cde contains anti-D. to prepare suitable anti-D reagent, which cell would be best for adsorption

cord testing results below. father is B (dce/dce). which antibody is mostly likely to cause positive DAT

neonate will be transfused for first time w/ O red cells, which is appropriate compatibility testing

based on KB results, which formula is used to determine volume of fetomaternal hemorrhage

which is most helpful to confirm weak ABO subgroup

patient serum react w/ 2/3 screen cells at AHG. 8/10 units are incompatible at AHG. all rxn are enhanced by enzymes. why

one of the most effective methods for elution of warm autoantibodies from rbc utilizes

what is the most likely cause of ABO discrepancy

serological results on untransfused patient are likely due to

mixed leukocyte culture is a biological assay for detecting which of the following

ABO HDFN differs from RH HDFN in that

ABO-hemolytic disease of newborn

autoantibodies demonstrating blood group specificity in warm autoimmune hemolytic anemia are associated w/ what group

what is the appropriate course of action for this postpartum sample

which is the correct interpretation of saliva neutralization testing

the main purpose of performing antibody titers from prenatal immunized women is to

at IAT, there is no agglutination btwn patient serum & screening cells. one of 3 donors is incompatible. why

which unit should be selected for exchange transfusion if newborn is group A, Rh+ & mother is group A, Rh+ w/ anti-c

how do you solve this problem

group A Rh+ infant of group O Rh+ mom has weak + DAT & moderate elevated bilirubin 12 hours after birth. why