Immuno Pre-Midterm (SGU SVM)

What is the main site of antigen presentation to lymphocytes?

this surface molecule is used to define subsets of lymphocytes

which of the following present peptide fragments from protein antigens to T-cells and CTLs

characteristics of viruses are:

which of the following can only recognize an antigen in the context of self-mhc molecules

Pyoderma is an example of

everyone in the animal kingdom (verterbrates and invertebrates) has MHC genes

MHC genotypes do not cause disease but are involved in disease risk.

Which are considered Phagocytic cells

Haptens are antigens <1000 Da in size. Which of these are haptens?

An antibody has a (Y) shaped structure. What is the role of the top (V) Fab part and lower (I) Fc part?

a virus must ____ to replicate

Macrophages ahve relativly short life spans in while neutorphils can live for months or years

What is defined as the primary activators of the innate immune system, as well as recognize invadors/tissue damage

The complement system contains cells

viral proteins are

which of the following can only be expressed on APCs

Which pathway(s) include Mannose-binding lectin

which of the follwing are nonmicrobial antigens

Which of these would make a BAD immunogen? (>1)

What is the defintion(s) of complement proteins?

this is made by a pathogen outside of the host cell but then killed inside a different cell

What is true regarding thymocytes:

Which pathway(s) are activated by IgG or IgM antibodies?

Pattern Recognition Receptors (PRRs) are a type of Toll-like Receptor(TLRs)

Whic is NOT a site of lymphocyte development (primary lymphoid organs)?

most parasites are included as this kind of pathogen

With pathway includes the Lectin Pathway?

How do viral endogenous antigens end up in the exogenous antigen pathway?

C1 binds to which region of an antibody during complement "fixation"?

Which cells can identify and kill invaders?

amino acids determine which MHC molecuule an animal can produce

What characteristics below fall under Humoral immunity?

the flagellum of some bacteria makes them poorly immunogenic

What is the name of immature neutrophils

TRUE or FALSE B-cells and antigens combine to create antibodies in the Humoral Immune Response?

How long do surviving T-lymphocytes remain in thymus to mature?

Fill in the blank: effector B-cells are _________ and can make _______.

Steroids are great for reducing inflammation but they can also downregulate which kind of cells?

which of the following could cause extinction of a population

IgG is the more efficiant immunoglobin because of its plantar formation

We have natural antibodies that arise from no previous infection/exposure. What antibodies would Type O blood have?

The Membrane Attack Complex is only a part of the classical pathway

What cell surface molecules promote adherence of the cell to various different things (ex. endothelium)

Which immune system cells generate B and T lymphocytes that express billions of unique receptors

What cell is the primary antigen presenting cell

M bovis is an example of

What is the END GOAL of the complement cascade? (1)

Antibodies are (2)

Professional antigen presenting cells involve

B-lymphocytes fall under what kinds of immunity

Which of these is the most immunogenic?

Select all of the correct statements regarding the presentation of exogenous antigens by MHC class II:

TRUE or FALSE Cytotoxic T-cells and T Helper cells help kill extracellular antigens

Complent Proteins are (2)

Innate immunity is the basis of vaccines, and helps prime the body for future antigens

these pathogens can be viruses

Which macrophage cytokine acts on T-cells and Natural Killer cells?

when m. bovis is killed, its molecules are

Select the correct matches:

these cells can only take up antigen that their receptors recognize

B-cells always need help from t helper cells

What kind of epitope is this?

MHC molecules can present multiple peptides at one time

TRUE or FALSE antibody and immunoglobulin mean the same thing

A stressed cat can be susceptable to nutrophobia

Pathogens resistant to lysosomes or can inhibit phagolysosomal fusion can survive IN macrophages

Multiple cells can make the same cytokine

Complement proteins are a part of the INNATE immune system only

What can a cytokine do?

These microbes replicate outside host cells

Hummoral and cell mediated immunity are able to communicate with one another

In the Complement Cascade C3b acts as an opsonin which leads to increased phagocytosis

What is the name for the generation of diverse lymphocytes with different TCRs?

the following processes and presents antigen in lymph tissue

How are lymphocytes selected to recognize foreign antigens only?

get pairing

Aquired immunity works faster than innate immunity because of its excellent memory

What cells are considered Sentinel cells?

Where do B cells mature and differentiate in birds?