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Kerathootics Exam I
Protopic
Tapinarof (VTAMA) Minimum age to treat dermatitis?
Kerathootics Exam I
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1
Tapinarof (VTAMA) Minimum age to treat dermatitis?
> 2 years
> 9 years
> 3 months
> 6 months
2
Protopic
Lebrikizumab
Pimecrolimus
Tacrolimus
Tralokinumab
3
Which nonpharmacologic treatments are common to Psoriasis, Rosacea, and Dermatitis?
Avoid triggers
Moisturizers
Stress reduction
Wear sun protection
4
Which antiarrhythmic drugs need hospitalization for initiation due to QT monitoring?
Ibutilide
Amiodarone
Sotalol
Dofetilide
5
If a patient has gout and hyperkalemia which meds should not be used for hypertension?
ACE/ARB
Thiazides
Loop diuretics
MRAs
6
PDE4 inhibitor used in plaque psoriasis and psoriatic arthritis:
Deucravacitinib (Sotyktu)
Apremilast (Otezla)
Etanercept (Enbrel)
Brodalumab (siliq)
7
First line for mild to moderate symptomatic atrioventricular tachycardia.
Splash face with ice water
Valsalva maneuver
DCC
Vagal massage
8
Which P2Y12 inhibitors are reversible
Cangrelor
Clopidogrel
Ticagrelor
Prasugrel
9
Minimum age for Tapinarof (Vtama)
6 years +
2 months +
12 years +
18 years +
10
psoriatic disease worsens/increases the chance of getting all of these comorbidities except:
Psoriatic arthritis
CVD
MDD
Hypotension
11
A subacute stent thrombosis is one that occurs ___ after a stent is installed.
24hrs-30days
more than 30 days after to 1 year
more than a year after stent
0-24hrs
12
A patient comes into the hospital without a PCI lab and EKG shows it's a NSTEMI.
Can start P2Y12 and Aspirin
Give aspirin and LMWH
Give fibrinolytics
Give alteplase and P2Y12
13
Which one is ST segment depression?
A
D
B
C
14
which treatment option is done in office and uses zinc to surround the plaque in order to protect healthy skin?
Keratolytic therapy
Coal Tar therapy
Topical retinoids
Anthralin therapy
15
High intensity statins lower LDL by
more than 50%
more than 32%
more than 60%
about 32-49%
16
Roflumilast (Zoryve) Minimum age to treat dermatitis?
> 9 years
>18 years
> 12 years
> 6 years
17
How do you diagnose peripheral artery disease?
Leg pain while exercising or resting
Leg pain at rest but not exertion
Wait for symptoms of a PE
BP of arm and ankle to compare difference
18
For a patient with heart failure which options are not usable for hypertension?
CCB
ARB
Beta blocker
ACE
19
Which of these are part of the 4D of classification?
Diet
Drugs
Diseases
Disorders
20
patient is anticipating knee surgery 5 months from now. This patient is getting a stent, what type of stent is best?
Drug eluting stent
Bare metal stent
21
17% ASCVD risk would fall under this category. assuming age:40-75, and LDL is 70-189mg/dL.
High risk
Low risk
Intermediate risk
Borderline risk
22
It is acceptable to to allow patients to remain in AF if they are rate controlled and:
on appropriate antithrombotic therapy
no diabetes
BP <110
age: 18-26
23
Talkoinumab (Adbry) Minimum age to treat dermatitis?
12-17 years
> 18 years
>2 years
> 9 years
24
which conditions are likely to lead to Psoriasis in specifically pediatrics?
NSAIDS
Psychogenic stress
Tattoos (Trauma)
Streptococcal infections
25
what is the lifetime risk of hypertension?
75%
13%
55%
90%
26
Tazarotene (Tazorac) is teratogenic and application covering more than 20% BSA can result in systemic absorption.
False
True
27
Why is fibrate therapy given to patients with TG >500mg/dL other than to lower the TGs?
The avoid hepatic disfunction
Increased risk of myopathy while on statins
Prevents acute pancreatitis
To prevent inaccurate LDL calculations while on a statin
28
Which med will help A patient with elevated BP, bilateral renal stenosis, renal failure, T2 diabetes, and ankle edema.
Fosinopril
Candesartan
Torsemide
Hydrochlorothiazide
29
Which class of antiarrhythmic drugs cannot be used in atrial arrythmias?
Ia
IV
Ib
III
30
How long after initiating DAPT would a patient be able to change to a single medication?
6 months
3 months
12 months
stay on DAPT indefinitely
31
If atopic dermatitis is unresponsive to topical corticosteroids, what is the second line?
TCAs
Topical calcineurin inhibitors
Systemic corticosteroids
32
For very high risk individuals what threshold should be the goal of LDL levels?
<70mg/dL
<90mg/dL
<110mg/dL
<130mg/dL
33
Of the topical treatments for rosacea with inflammatory papules/pustules, which is flammable?
Ivermectin (Soolantra)
Azelaic acid (Finacea)
Minocycline foam (ZILXI)
Metronidazole
34
how long after initiation or dose adjustment of a statin should adherence and lipid measurements be assessed?
2 years
1 week
4 - 12 weeks
every 3 - 12 months
35
After starting a statin and lifestyle changes Tervor is experiencing muscle pain. LDL: 95, HDL: 60, TG: 136, CK: 1400
Rhabdomyolysis
90% Ventricular occlusion
Just soreness from new lifestyle changes and activity.
Myalgia
36
Rate control in hemodynamically stable patients with decompensated HF should be?
Beta blockers
Verapamil and diltiazem
Digoxin
IV amiodarone
37
What is the first line for hemodynamically unstable Afib or flutter with 34% LVEF?
Aspirin and clopidogrel
DCC
Not DCC due to risk of throwing a clot. use a beta blocker or CCB
Digoxin and betablocker
38
What level is optimal for LDL
<190mg/dL
<130mg/dL
<200mg/dL
<100mg/dL
39
An arrythmia is an abnormal rhythm of cardiac conduction accompanied by rapid or slow HRs
False
True
40
Adverse effect of Sotyktu
Malignant hyperthermia
Lowered triglyceride levels
Renal toxicity
HSV activation
41
For every 1% decrease in HDL there is a 2-3% increase in the risk of CHD.
True
False
42
which is contraindicated in hemorrhagic or ischemic stroke
Ticagrelor
Prasugrel
Alteplase
Clopidogrel
43
What arrythmia is this?
PVCs
VF
Atrial fibrillation
Polymorphic VT
44
Which LDL lowering agents increase the risk of tendon rupture and benign prostatic hyperplasia?
Atorvastatin
Rosuvastatin
Bempedoic acid
Fenofibrate
45
Of these, which are subQ injections?
Talkoinumab
Roflumilast
Dupilumab
Ruxolitinib
46
Which agent would be able to help a patient with relatively normal lipid panel except elevated TG of 864mg/dL
Colesevelam
Gemfibrozil
Colestipol
Cholestyramine
47
Hypertensive patient with stable angina, which treatment would best benefit this patient? (including add on therapy)
Beta blocker or ACE/ARB with a thiazide
Beta blocker with an ACE and ARB
Beta blocker or ACE/ARB with a CCB
Thiazide with MRA and ACE
48
Diastolic BP is determined during contraction of the ventricles.
True
False
49
Thickened skin and surface nodularities
Erythematotelangiectatic
Phymatous
Demodex
Papulopustular
50
Chronic NSAID use and ACE inhibitors cause damage to the kidney.
True
False
51
Anticoagulation is preferred in stroke risk patients if their score is greater than 1 for males and 2 for females.
True
False
52
If a high ASCVD risk patient is on a max dose high intensity statin without improvement what are the next options?
Add a PCSK9 mab
Add another statin
Add ezetimibe
change to a different statin
53
Black box warning for calcineurin inhibitors?
Increased chance of warts
Steven Johnson syndrome
Agranulocytosis
increased risk of skin cancers
54
Low and slow dosing does not matter when it comes to severe hypercholesterolemia.
False
True
55
Photosensitivity that can spread to spots not exposed is:
Photoallergic
Phototoxic
56
Masked hypertension is:
A patient has elevated BP only during in office visits
Having hypertension at home but not during office visits
Only having hypertension while laying down
When a patient shows no symptoms of hypertension
57
What Medications or changes can be made to help prevent the flushing due to niacin?
Take on an empty stomach
Take ibuprofen 30 min before dose
Exercise for 30-40 min after dose
Take aspirin 30 min before dose
58
Topical steroids are rated on a scale of 1-7 (7 being most potent)
False
True
59
A patient has psoriasis covering 12% BSA, PASI of 11 and a DLQI of 11
Moderate
Mild
Severe
60
which is not a defining characteristic of rosacea?
Telangiectasia
Pustules
Arythema
Comadones
61
Rate control is favored in younger patient populations.
True
False
62
Rate control, Rhythm control, Anticoagulants, and lifestyle modifications are the goals for treating afib.
False
True
63
which statin undergoes glucuronidation with negligible CYP450 metabolism?
Fluvastatin
Pravastatin
Rosuvastatin
Simvastatin
64
which of these just treat the redness symptom of rosacea erythema
Crisaborole (Eucrisa)
Oxymetazoline HCl (Rhofade)
Brimonidine (Mirvaso)
Tapinarof (VTAMA)
65
if the EKG appears to show multiple vessel occlusions. What medications should not be given?
Clopidogrel
Morphine
Ticagrelor
Aspirin
66
Which calcineurin inhibitor can be used for a 17yo with mild psoriasis?
Tacrolimus 0.03% oint
Pimecrolimus 1% cream
Pimecrolimus 5% cream
Tacrolimus 0.1% oint
67
Primarily composed of TG and carries TG and lipids to skeletal muscle and adipose tissue.
LDL
Chylomicrons
HDL
VLDL
68
A patient has BP 150/90mmHg and HR 95 bpm with chest pain not resolving on nitroglycerin.
Give Enoxaparin until patient can get to PCI lab
give low dose PO beta blocker
Start P2Y12 inhibitor
Administer IV morphine
69
Vit D3 analogs can have systemic absorption past application greater than 30% BSA
False
True
70
Atrial contraction occurs in what interval?
ST
PQ
PR
QRS
71
Goals of Psoriasis treatment are:
Decrease BSA
Improve patient quality of life
Eliminate plaques and scales
Avoid flare ups
72
Most potent topical corticosteroid:
Desonide
Mometasone
Hydrocortisone
Betamethasone
73
which types of Psoriasis are potentially life threatening?
Pustular
Plaque
Erythrodermic
Guttate
74
Aspirin can be used for primary prevention of ASCVD events.
True
False
75
Betablockers effects are less pronounced in elderly due to decreased sympathetic tone.
False
True
76
Bob is meeting his BP goal while taking 4 antihypertensive agents. Does Bob have resistant hypertension?
No
Yes
77
which TNFa inhibitor is for only UC and psoriatic arthritis but not psoriasis?
Adalimumab (humira)
Infliximab (Remicade)
Certolizumab pegol (cimzia)
Golimumab (simponi)
78
A 55 year old person with an LDL of 84mg/dL and 6% ASCVD risk should:
Discuss lifestyle changes and initiate moderate intensity statin
Start a high intensity statin and begin lifestyle changes
Discuss lifestyle changes to reduce ASCVD risk
Be initiated on a high intensity statin
79
For resistant rosacea:
Erythromycin
Adapalene
Permethrin
tretinoin
80
Troponin will be elevated in both unstable angina and an NSTEMI or STEMI.
True
False
81
what factor indicates arterial wall tension?
Mean arterial pressure
Systolic BP
Diastolic BP
Pulse pressure
82
At what levels do TGs have to be at for calculating LDL to no longer be accurate?
TG >1000mg/dL
TG >500mg/dL
TG >650mg/dL
TG >400mg/dL
83
What are the first line agents of stable angina?
Beta blockers
Vascular CCB
Cardiac CCB
Nitrates
84
DLQI is a measure how impactful psoriasis has been over the past week on a scale of 1-30.
True
False
85
Treatment of supraventricular tachycardias depend on range of the QRS interval and severity of symptoms.
True
False
86
Minimum age for Roflumilast (Zoryve)
6 months +
1 year +
12 years +
6 years +
87
What conditions are necessary to recommend a lifestyle modification and monotherapy?
Elevated BP
Stage 2 hypertension
Stage 1 hypertension and ASCVD risk >10%
Stage 2 hypertension and ASCVD risk >10%
88
Major carrier of cholesterol in circulation. Carries 60-70% of total blood cholesterol.
Chylomicrons
HDL
LDL
VLDL
89
Main side effect of Prazosin
renal toxicity
orthostatic hypotension
Angioedema
hypoglycemia
90
Ruxolitinib (Opzelura) Minimum age to treat dermatitis?
> 6 months
> 12 years
> 9 years
> 2 years
91
Primary/ essential hypertension is commonly caused by disease states and medications.
False
True
92
What additional benefits do statins have besides their LDL lowering?
Myalgia
Reduces bile acid secretion
BP lowering
Pleotropic effect
93
In both nonstructural heart disease and structural, catheter ablation is an option if nothing else works
True
False
94
which atopic dermatitis agent has a black box warning for TB HCV/HBV infection reactivation?
Ruxolitinib (Opzelura)
Roflumilast (Zoryve)
Tapinarof (VTAMA)
Crisaborole (Eucrisa)
95
What are acceptable BSA values for treatment of psoriasis?
< or = 1%
< or = 3%
0%
<10%
96
A patient has a PASI score of 8.5, what category does this fall under?
Severe
Mild
Moderate
97
Symptoms of pre eclampsia are?
Proteinuria
seizures
Hypotensive emergency
New onset hypertension
98
What is the onset time of steven johnson syndrome and toxic epidermal necrolysis after exposure to the offending drug?
3-4 days
30min - 1 hour
12-24 hours
7-14 days
99
A patient with a BP of 117/83 falls under what classification?
Stage 2 hypertension
Elevated
Normotensive
Stage 1 hypertension
100
PASI scoring is categorized by Mild: less than 8, Moderate: 8-10, severe: greater than 10
True
False
101
What is the first thing other than CPR that is done in management of acute VF
install IV or IO access
Give oxygen and attach defibrillator
Epinephrine every 3-5 min
Amiodarone
102
a patient has trouble taking meds PO but doesn't struggle with aspirin what is the best option for DAPT
Aspirin + Cangrelor
Aspirin + Ticagrelor
Aspirin + Prasugrel
Aspirin + Clopidogrel
103
A patient is having flushing and cannot figure out which of their meds are causing this, below are the meds:
Bempedoic acid
Atorvastatin
Niacin
Gemfibrozil
104
When is thrombolytic/fibrinolytic therapy considered?
No access to a PCI lab within 120 mins
Only considered for NSTEMI
Only considered when a multi vessel STEMI was given a P2Y12 inihibtor
only considered for STEMI with no access to PCI lab within 120 min
105
Very high risk ASCVD is categorized as:
More than 2 major ASCVD events
1 Major ASCVD event and more than 2 high risk conditions
1 or more Major ASCVD events
4 or more high risk conditions
106
dermatologic drug reaction occurs within 30min - 2 hours of administration and is characteristic of anaphylaxis.
Immune complex mediated
IgE mediated
IgM mediated
IgG mediated
107
Which lifestyle modification has a large impact on BP and is easy to keep track of?
Heart healthy diet
Moderation of alcohol intake
Increased physical activity
Weight loss
108
If a patient using nitroglycerin does not get a headache, it may be old or not working.
False
True
109
Guttate psoriasis is caused by strepto infections.
False
True
110
2nd generation Stents are made of:
Cobalt
Platinum
Chromium
Stainless steel
111
Elidel
Pimecrolimus
Upadacitinib
Lebrikizumab
Crisaborole
112
Which of these disease states will result in increased TG and increased HDL?
Obstructive liver disease
None of these
Alcoholism
Diabetes mellitus
113
What labs or test should be ordered for a patient complaining of chest pain?
LDL level
ECG
Troponin level
D Dimer
114
which BRM can treat pustular arthritis?
Ustekinumab (stelara)
Certolizumab pegol (Cimzia)
Infliximab (Remicade)
Spesolimab (Sevigo)
115
Sensitivity to UV unrelated to dosing is:
Phototoxic
Photoallergic
116
A patient is not responding well to their past dose increases of lisinopril (current medium dose). Next action?
Leave the lisinopril dose and add a low dose CCB
Increase the dose of lisinopril to the max dose
Discontinue lisinopril and begin low dose betablocker and ARB
Add an additional max dose diuretic
117
Which condition is hyperproliferative and results in skin turnover happening 10-20x normal skin?
Dermatitis
Rosacea
Psoriasis
cystic fibrosis
118
Choose what treatment best fits a patient with psoriatic arthritis, Crohn's and a latex allergy.
Secukinumab (Cosentyx)
Risankizumab (Skyrizi)
Tildrakitzumab (Ilumya)
Brodalumab (Siliq)
119
what are the 2 factors in choosing treatment for hypertension?
Degree of elevation
Morbidity reduction %
Compelling indications
Mortality reduction %
120
Which Il-17 inhibitor may decrease CV risk but can exacerbate Crohns and UC?
Bimekizumab (Bimzelx)
Secukinumab (Cosentyx)
Ixekizumab (Taltz)
Brodalumab (Siliq)
121
non Biologic psoriasis treatments increase the risk of reactivation for TB, HBV, HCV, and HIV.
True
False
122
Patients who have afib for greater than 48 hours are at great risk of throwing a clot.
False
True
123
What is the max score for PASI
22
30
72
100
124
First line topical agents: Psoriasis.
VIT D3 analogs
Topical corticosteroids
Tazarotene
Anthralin
125
This patient has diabetes mellitus and an ASCVD risk of 23%. what therapy is best?
Pravastatin 40mg + ezetimibe
Rosuvastatin 20mg
Atorvastatin 20mg
Atorvastatin 80mg + ezetimibe
126
A patient would like to improve their moderate psoriasis but does not trust prescription meds, what options may help?
Aloe Vera
Fish oil/ Omega 3 fatty acid supplementation
Saline bath and UV
Zinc
127
Which one of these conditions if met would warrant systemic therapy?
BSA >10%
Effected areas are face, palms, scalp, or nails.
DLQI of 28-30
Failure to treat on topicals
128
What monitoring is common to all BRMs?
monitoring for suicidal ideations
Infections
Latent TB
Hep B and C
129
Fibrin rich clots (Red clots) are primarily veinous and best treated by:
Antiplatelets
Anticoagulants
130
how many adults in the US have hypertension?
100%
1/5
1/3
1/2
131
Dupilumab (Dupixent) Minimum age to treat dermatitis?
> 3 months
12-17 years
> 6 months
> 2 years
132
other than exercise to stress the heart in order to visualize occlusions, what meds can be used to simulate exercise?
Regadenoson
Adenosine
Dobutamine
Dipyramidole
133
Reentrant tachycardias are caused by an abnormality in impulse generation.
False
True
134
Which Il-17 inhibitor increases chances of suicidal ideation?
Brodalumab (Siliq)
Bimekizumab (Bimzelx)
Secukinumab (Cosentyx)
Ixekinumab (Taltz)
135
On an EKG, Atrial fibrillation will have:
Saw tooth pattern
Inverted T wave
Multiple P waves for each QRS interval
No distinguishable P wave
136
Crisaborole (Eucrisa) Minimum age to treat dermatitis?
> 9 years
> 3 months
> 12 years
> 2 years
137
If a patient chooses to try lifestyle changes, how long do you wait before checking in again?
6 weeks
3-4 weeks
3 months
6 months
138
What type of arrythmia is this?
Monomorphic ventricular tachycardia
Atrial flutter
Atrial fibrillation
Premature ventricular contractions
139
which type of fish oil does not have the adverse effect of fish burps?
DHA
EPA and DHA
EPA
140
Which drug would best treat psoriasis in a patient who has class III HF
Infliximab (Remicade)
Secukinumab (Cosentyx)
Adalimumab (Humira)
Golimumab (Simponi)
141
what is the MAP and pulse pressure of a patient whose BP is 150/120
MAP: 130, Pulse pressure: 30
MAP: 66.7, Pulse pressure: 33.3
MAP 115, Pulse pressure 90
MAP: 135, Pulse pressure: 50
142
Which are indicated for homozygous familial hypercholesteremia?
Ezetimibe
Simvastatin
Evinacumab-dgnb
Evolocumab
143
A patient with these comorbidities: ankle edema, hypertension, and Raynaud's phenomenon would best be treated by
Nifedipine
Hydrochlorothiazide
Diltiazem
Verapamil
144
which have the highest reduction in cardiac events?
Aspirin
PCSK9 mabs
Statins
Antihypertensives
145
a patient with chest pain was given nitroglycerin and now has a SBP of 70mmHg and is cold to the touch.
Patient is in cardiogenic shock due to taking a PDE 2 hours prior
Patient is just taking a nap
Patient is in cardiogenic shock due to beta blockers and nitrates
Morphine or a betablocker should have been given instead of a nitrate
146
Which treatment would be best for a patient who is currently pregnant and has an allergy to latex?
Adalimumab (Humira)
Certolizumab (Cimzia)
Spesolimab (Sevigo)
Secukinumab (Cosentyx)
147
If mild or moderate plaque psoriasis cases are unresponsive to topical agents what is the next suggestion?
Add moisturizer to routine as needed
Add phototherapy
Add a systemic agent
discontinue topical agent and switch to just systemic agent
148
Type 2 MI is based on O2 demands and no coronary artery thrombosis is present.
False
True
149
which Il-17 inhibitor is not indicated for psoriatic arthiritis and is contraindicated in crohns
Ixekizumab (Taltz)
Brodalumab (Siliq)
Secukinumab (Cosentyx)
Bimekizumab (Bimzelx)
150
Approximately how many adults 20 years or older have a total cholesterol higher than 200mg/dL?
30%
49%
58%
67%
151
in adults 40-75 years old regardless of ASCVD risk with diabetes, moderate intensity statin therapy is indicated.
True
False
152
To manage chest pain in ACS when can IV Morphine not be used?
Hypotensive
LV dysfunction
Hemodynamically unstable
BP >140mmHg
153
If suspected fungal infections do not use steroids for treatment of psoriasis.
False
True